Sherin Peter S, López-Duarte Ismael, Dent Michael R, Kubánková Markéta, Vyšniauskas Aurimas, Bull James A, Reshetnikova Evdokiya S, Klymchenko Andrey S, Tsentalovich Yuri P, Kuimova Marina K
International Tomography Center SB RAS , Institutskaya Street 3A , 630090 , Novosibirsk , Russia . Email:
Department of Natural Sciences , Novosibirsk State University , Pirogova Street 2 , 630090 , Novosibirsk , Russia.
Chem Sci. 2017 May 1;8(5):3523-3528. doi: 10.1039/c6sc05369f. Epub 2017 Feb 14.
The plasma membranes of cells within the eye lens play an important role in metabolite transport within the avascular tissue of the lens, maintaining its transparency over the entire lifespan of an individual. Here we use viscosity-sensitive 'molecular rotors' to map the microscopic viscosity within these unusual cell membranes, establishing that they are characterised by an unprecedentedly high degree of lipid organisation.
眼晶状体中的细胞的质膜在晶状体无血管组织内的代谢物运输中起着重要作用,在个体的整个生命周期内维持其透明度。在这里,我们使用对粘度敏感的“分子转子”来绘制这些特殊细胞膜内的微观粘度,确定它们具有前所未有的高度脂质组织特征。