Zhang Nixiao, Liu Tong, Tse Gary, Yu Shuyu, Fu Huaying, Xu Gang, Zhou Changyu, Zhang Chengzong, Li Guangping
Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, P.R. China.
Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, SAR, P.R. China.
Oxf Med Case Reports. 2017 May 30;2017(5):omx014. doi: 10.1093/omcr/omx014. eCollection 2017 May.
Brugada phenocopy (BrP) refers to a group of clinical conditions that have etiologies distinct from Brugada syndrome (BrS). Although both demonstrate features of ST-segment elevation in the right precordial leads on the electrocardiogram (ECG), one must be distinguished from the other as their treatment options are different. We report a male patient who presented with recurrent syncope with a Brugada and a S1Q3T3 pattern on the ECG. Acute pulmonary embolism (APE) complicated by BrS was suspected. Twenty-four hours Holter monitoring did not demonstrate any evidence of ventricular arrhythmias. Computed tomography pulmonary angiogram confirmed the presence of an APE. He was treated with low molecular weight heparin and a repeat ECG taken the next day showed resolution of the Brugada and S1Q3T3 patterns. This case report illustrates that APE and BrS can present with similar clinical and electrocardiographic features of recurrent syncope and Brugada pattern, respectively.
Brugada 综合征拟表型（BrP）指的是一组病因与 Brugada 综合征（BrS）不同的临床病症。尽管二者在心电图（ECG）上均表现为右胸导联 ST 段抬高，但由于它们的治疗方案不同，必须加以区分。我们报告一例男性患者，其反复出现晕厥，心电图显示有 Brugada 波和 S1Q3T3 波形。怀疑为急性肺栓塞（APE）合并 BrS。24 小时动态心电图监测未显示任何室性心律失常的证据。计算机断层扫描肺动脉造影证实存在 APE。给予低分子肝素治疗，次日复查心电图显示 Brugada 波及 S1Q3T3 波形消失。本病例报告表明，APE 和 BrS 可分别表现出类似的反复晕厥临床特征及 Brugada 波心电图特征。
