扩大皮肤干细胞生态位。
T Expand the Skin Stem Cell Niche.
机构信息
Departments of Molecular, Cellular and Developmental Biology and Dermatology, Yale University, New Haven, CT 06520, USA.
Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY 10065, USA.
出版信息
Dev Cell. 2017 Jun 5;41(5):455-456. doi: 10.1016/j.devcel.2017.05.020.
PMID:28586641
Abstract
Regulatory T cells (T) are emerging as an essential stem cell niche component that promotes wound repair in adipose, muscle, and lung tissues. Recently in Cell, Ali et al. (2017) report that skin resident T facilitate the proliferation and differentiation of hair follicle stem cells through Notch signaling.
摘要
调节性 T 细胞（T 细胞）正在成为促进脂肪、肌肉和肺部组织伤口修复的必不可少的干细胞龛组成部分。最近，Ali 等人（2017）在《细胞》杂志上报道称，皮肤驻留 T 细胞通过 Notch 信号促进毛囊干细胞的增殖和分化。
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