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患有类似Chiari畸形和脊髓空洞症的骑士查理王小猎犬在时空步态特征上具有更大的变异性。

Cavalier King Charles Spaniels with Chiari-like malformation and Syringomyelia have increased variability of spatio-temporal gait characteristics.

作者信息

Olsen Emil, Suiter Emma Jane, Pfau Thilo, McGonnell Imelda M, Matiasek Kaspar, Giejda Anna, Volk Holger Andreas

机构信息

Department of Clinical Science and Services, The Royal Veterinary College, Hawkshead Lane, Hatfield, AL9 7TA, UK.

Department of Clinical Sciences, Faculty of Veterinary Medicine, Cornell University, 930 Campus Road, Ithaca, N.Y., 14850, USA.

出版信息

BMC Vet Res. 2017 Jun 6;13(1):159. doi: 10.1186/s12917-017-1077-5.

DOI:10.1186/s12917-017-1077-5
PMID:28587601
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5461676/
Abstract

BACKGROUND

Chiari-like malformation in the Cavalier King Charles Spaniel is a herniation of the cerebellum and brainstem into or through the foramen magnum. This condition predisposes to Syringomyelia; fluid filled syrinxes within the spinal cord. The resulting pathology in spinal cord and cerebellum create neuropathic pain and changes in gait. This study aims to quantify the changes in gait for Cavalier King Charles Spaniel with Chiari-like malformation and Syringomyelia.

METHODS

We compared Cavalier King Charles Spaniel with Chiari-like malformation with (n = 9) and without (n = 8) Syringomyelia to Border Terriers (n = 8). Two video cameras and manual tracking was used to quantify gait parameters.

RESULTS AND CONCLUSIONS

We found a significant increase in coefficient of variation for the spatio-temporal characteristics and ipsilateral distance between paws and a wider base of support in the thoracic limbs but not in the pelvic limbs for Cavalier King Charles Spaniels compared with the border terrier.

摘要

背景

查理士王小猎犬的类Chiari畸形是小脑和脑干疝入枕骨大孔或穿过枕骨大孔。这种情况易引发脊髓空洞症，即脊髓内充满液体的空洞。脊髓和小脑由此产生的病变会导致神经性疼痛和步态改变。本研究旨在量化患有类Chiari畸形和脊髓空洞症的查理士王小猎犬的步态变化。

方法

我们将患有（n = 9）和未患有（n = 8）脊髓空洞症的类Chiari畸形查理士王小猎犬与边境梗犬（n = 8）进行比较。使用两台摄像机和手动跟踪来量化步态参数。

结果与结论

我们发现，与边境梗犬相比，查理士王小猎犬的时空特征变异系数、爪子之间的同侧距离显著增加，且胸肢的支撑面更宽，但盆腔肢并非如此。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f34c/5461676/7f259f97bfb9/12917_2017_1077_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f34c/5461676/7f259f97bfb9/12917_2017_1077_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f34c/5461676/7f259f97bfb9/12917_2017_1077_Fig1_HTML.jpg

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