Kakarmath Sujay S, Zack Rachel M, Leyna Germana H, Fahimi Saman, Liu Enju, Fawzi Wafaie W, Lukmanji Zohra, Killewo Japhet, Sacks Frank, Danaei Goodarz
Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
BMJ Open. 2017 Jun 6;7(5):e015028. doi: 10.1136/bmjopen-2016-015028.
To assess the dietary determinants of serum total cholesterol.
Cross-sectional population-based study.
Peri-urban region of Dar es Salaam, Tanzania.
347 adults aged 40 years and older from the Dar es Salaam Urban Cohort Hypertension Study.
Serum total cholesterol measured using a point-of-care device.
Mean serum total cholesterol level was 204 mg/dL (IQR 169-236 mg/dL) in women and 185 mg/dL (IQR 152-216 mg/dL) in men. After adjusting for demographic, socioeconomic, lifestyle and dietary factors, participants who reported using palm oil as the major cooking oil had serum total cholesterol higher by 15 mg/dL (95% CI 1 to 29 mg/dL) compared with those who reported using sunflower oil. Consumption of one or more servings of meat per day (p for trend=0.017) and less than five servings of fruits and vegetables per day (p for trend=0.024) were also associated with higher serum total cholesterol. A combination of using palm oil for cooking, eating more than one serving of meat per day and fewer than five servings of fruits and vegetables per day, was associated with 46 mg/dL (95% CI 16 to 76 mg/dL) higher serum total cholesterol.
Using palm oil for cooking was associated with higher serum total cholesterol levels in this peri-urban population in Dar es Salaam. Reduction of saturated fat content of edible oil may be considered as a population-based strategy for primary prevention of cardiovascular diseases.
评估血清总胆固醇的饮食决定因素。
基于人群的横断面研究。
坦桑尼亚达累斯萨拉姆的城郊地区。
来自达累斯萨拉姆城市队列高血压研究的347名40岁及以上的成年人。
使用即时检测设备测量血清总胆固醇。
女性的平均血清总胆固醇水平为204mg/dL(四分位间距169 - 236mg/dL),男性为185mg/dL(四分位间距152 - 216mg/dL)。在调整了人口统计学、社会经济、生活方式和饮食因素后,报告使用棕榈油作为主要烹饪油的参与者的血清总胆固醇比报告使用葵花籽油的参与者高15mg/dL(95%置信区间1至29mg/dL)。每天食用一份或多份肉类(趋势p值 = 0.017)以及每天食用少于五份水果和蔬菜(趋势p值 = 0.024)也与较高的血清总胆固醇相关。同时使用棕榈油烹饪、每天食用超过一份肉类且每天食用少于五份水果和蔬菜,与血清总胆固醇高46mg/dL(95%置信区间16至76mg/dL)相关。
在达累斯萨拉姆的这个城郊人群中,使用棕榈油烹饪与较高的血清总胆固醇水平相关。减少食用油中的饱和脂肪含量可被视为基于人群的心血管疾病一级预防策略。