Okita Yoshiko, Masuda Norikazu, Mizutani Makiko, Kodama Yoshinori, Mori Kiyoshi, Mano Masayuki, Nakagawa Tomoyoshi, Nakajima Shin, Fujinaka Toshiyuki
Department of Neurosurgery, National Hospital Organization Osaka National Hospital, Osaka 540-0006, Japan.
Department of Surgery, Breast Oncology, National Hospital Organization Osaka National Hospital, Osaka 540-0006, Japan.
Mol Clin Oncol. 2017 Jun;6(6):960-962. doi: 10.3892/mco.2017.1233. Epub 2017 Apr 28.
We herein present the case of a 49-year-old female patient presenting with nausea and headache. The patient's medical history included breast cancer with bone and lymph node metastasis. Computed tomography (CT) examination revealed a high-density lesion in the right subdural space, suggesting hematoma. During surgery planned for subdural hematoma drainage, an en plaque subdural yellowish-white tumor was identified, without hematoma. Histopathological examination revealed metastatic breast cancer. The patient was administered predonisolone and her neurological symptoms gradually recovered. However, 12 days after the first operation, the clinical course was complicated by vomiting and rapid loss of consciousness. Emergency CT revealed that the subdural tumor had enlarged and decompression was performed as life-saving surgery. However, the patient's condition progressively deteriorated and she finally succumbed to the disease 2 months after the second operation. The aim of this study was to present the case of a patient with a large en plaque subdural tumor mimicking subdural hematoma and causing rapid loss of consciousness and cerebral herniation.
我们在此报告一例49岁女性患者,该患者出现恶心和头痛症状。患者既往病史包括乳腺癌伴骨和淋巴结转移。计算机断层扫描(CT)检查显示右侧硬膜下间隙有一个高密度病变,提示血肿。在计划进行硬膜下血肿引流手术期间,发现了一个硬膜下斑块状黄白色肿瘤,并无血肿。组织病理学检查显示为转移性乳腺癌。患者接受了泼尼松龙治疗,其神经症状逐渐恢复。然而,首次手术后12天,临床过程出现呕吐和意识迅速丧失的并发症。急诊CT显示硬膜下肿瘤增大,遂进行减压手术作为挽救生命的手术。然而,患者病情逐渐恶化,最终在第二次手术后2个月死于该病。本研究的目的是报告一例患者,其患有类似硬膜下血肿的大面积硬膜下斑块状肿瘤,导致意识迅速丧失和脑疝形成。