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确定维持晚期膀胱癌且身体状况不佳的高龄患者生活质量的最佳方法:一例病例报告。

Determining the optimum way to maintain quality of life for very elderly patients with advanced bladder cancer and poor performance status: A case report.

作者信息

Suzuki Kenjiro, Hanashima Fuminari, Shirotake Suguru, Kodaira Kiichiro, Nishimoto Koshiro, Takahashi Takao, Onishi Hideki, Oyama Masafumi

机构信息

Department of Uro-Oncology, Saitama Medical University International Medical Center, Saitama 350-1298, Japan.

Department of Urology, Suzuki Clinic, Chiba 289-2102, Japan.

出版信息

Mol Clin Oncol. 2017 Jun;6(6):968-970. doi: 10.3892/mco.2017.1236. Epub 2017 May 5.

Abstract

Locally advanced bladder cancer causes unpleasant symptoms such as irritative voiding symptoms, lower abdominal pain, gross hematuria and urinary retention, and lowers the quality of life. Treatment decisions in elderly patients may be difficult, as elderly patients are physically and psychologically different from younger patients. An 89-year-old male was referred to hospital for the treatment of an invasive bladder tumor with right hydronephrosis from tumor obstruction. The patient was elderly and did not have a good performance status; therefore curative radical cystectomy or chemotherapy was not indicated. Left retroperitoneoscopic ureterocutaneostomy was performed to alleviate gross hematuria and voiding difficulty. Intensity-modulated radiotherapy was administered 9 days after the surgery to control bleeding in the bladder tumor. After completing 8 days of radiotherapy, the patient was discharged from hospital. The patient exhibited no signs of either postrenal failure or gross hematuria for 7 months prior to mortality. Retroperitoneoscopic ureterocutaneostomy for very elderly patients with advanced bladder cancer with a poor performance status may be an important procedure for alleviating symptoms and improving quality of life.

摘要

局部晚期膀胱癌会引起诸如刺激性排尿症状、下腹部疼痛、肉眼血尿和尿潴留等不适症状,降低生活质量。老年患者的治疗决策可能较为困难,因为老年患者在身体和心理方面与年轻患者不同。一名89岁男性因侵袭性膀胱肿瘤伴肿瘤梗阻导致右肾积水而被转诊至医院治疗。该患者年事已高,身体状况不佳;因此,不适合进行根治性膀胱切除术或化疗。行左后腹腔镜输尿管皮肤造口术以缓解肉眼血尿和排尿困难。术后9天行调强放疗以控制膀胱肿瘤出血。完成8天放疗后,患者出院。在死亡前7个月,患者未出现肾衰竭或肉眼血尿迹象。对于身体状况不佳的高龄晚期膀胱癌患者,后腹腔镜输尿管皮肤造口术可能是缓解症状和提高生活质量的重要手术。

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