Peters Sanne A E, Woodward Mark, Jha Vivekanand, Kennedy Stephen, Norton Robyn
The George Institute for Global Health, University of Oxford, Oxford, UK.
The George Institute for Global Health, University of Sydney, Sydney, New South Wales, Australia.
BMJ Glob Health. 2016 Nov 1;1(3):e000080. doi: 10.1136/bmjgh-2016-000080. eCollection 2016.
Global efforts to improve the health of women largely focus on improving sexual and reproductive health. However, the global burden of disease has changed significantly over the past decades. Currently, the greatest burden of death and disability among women is attributable to non-communicable diseases (NCDs), most notably cardiovascular diseases, cancers, respiratory diseases, diabetes, dementia, depression and musculoskeletal disorders. Hence, to improve the health of women most efficiently, adequate resources need to be allocated to the prevention, management and treatment of NCDs in women. Such an approach could reduce the burden of NCDs among women and also has the potential to improve women's sexual and reproductive health, which commonly shares similar behavioural, biological, social and cultural risk factors. Historically, most medical research was conducted in men and the findings from such studies were assumed to be equally applicable to women. Sex differences and gender disparities in health and disease have therefore long been unknown and/or ignored. Since the number of women in studies is increasing, evidence for clinically meaningful differences between men and women across all areas of health and disease has emerged. Systematic evaluation of such differences between men and women could improve the understanding of diseases, as well as inform health practitioners and policymakers in optimising preventive strategies to reduce the global burden of disease more efficiently in women and men.
全球改善女性健康的努力主要集中在改善性健康和生殖健康方面。然而,在过去几十年中,全球疾病负担发生了显著变化。目前,女性中最大的死亡和残疾负担归因于非传染性疾病(NCDs),最显著的是心血管疾病、癌症、呼吸系统疾病、糖尿病、痴呆症、抑郁症和肌肉骨骼疾病。因此,为了最有效地改善女性健康,需要将足够的资源分配到女性非传染性疾病的预防、管理和治疗上。这样的方法可以减轻女性中非传染性疾病的负担,并且还有可能改善女性的性健康和生殖健康,因为这两者通常具有相似的行为、生物学、社会和文化风险因素。从历史上看,大多数医学研究是在男性身上进行的,并且这些研究的结果被认为同样适用于女性。因此,健康和疾病方面的性别差异和性别不平等长期以来一直不为人知和/或被忽视。由于参与研究的女性数量在增加,在健康和疾病的所有领域中,男性和女性之间具有临床意义的差异的证据已经出现。对男性和女性之间的这种差异进行系统评估,可以增进对疾病的理解,并为健康从业者和政策制定者提供信息,以便更有效地优化预防策略,减轻全球男性和女性的疾病负担。