Smulevich A B, Vorob'ev V Iu, Dubnitskaia E B, Maksimov V I, Novikov V N
Zh Nevropatol Psikhiatr Im S S Korsakova. 1985;85(1):94-100.
The authors analyze the results of psychopharmacotherapy of 120 patients with slowly progressive schizophrenia characterized by a high resistance to the treatment. Two new methods of the intensive therapy of such conditions (discrete and daily intravenous drip of tranquilizers in conjunction with low doses of neuroleptics) are described. The pharmacological and pharmacokinetic substantiation of each of the two techniques is presented. Clinical indications for their use have been elaborated.
作者分析了120例进展缓慢型精神分裂症患者的心理药物治疗结果,这类患者对治疗具有高度耐药性。文中描述了针对此类病症的两种强化治疗新方法(离散型和每日静脉滴注镇静剂并联合小剂量抗精神病药物)。介绍了这两种技术各自的药理学和药代动力学依据。阐述了其使用的临床指征。