Gallego Juan A, Perich Matthew G, Miller Lee E, Solla Sara A
Department of Physiology, Northwestern University, Chicago, IL 60611, USA; Neural and Cognitive Engineering Group, Centre for Robotics and Automation CSIC-UPM, Arganda del Rey 28500, Spain.
Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.
Neuron. 2017 Jun 7;94(5):978-984. doi: 10.1016/j.neuron.2017.05.025.
The analysis of neural dynamics in several brain cortices has consistently uncovered low-dimensional manifolds that capture a significant fraction of neural variability. These neural manifolds are spanned by specific patterns of correlated neural activity, the "neural modes." We discuss a model for neural control of movement in which the time-dependent activation of these neural modes is the generator of motor behavior. This manifold-based view of motor cortex may lead to a better understanding of how the brain controls movement.
对多个大脑皮层神经动力学的分析一直揭示出低维流形，这些流形捕获了相当一部分神经变异性。这些神经流形由相关神经活动的特定模式（即“神经模式”）所构成。我们讨论了一种运动神经控制模型，其中这些神经模式随时间的激活是运动行为的产生者。这种基于流形的运动皮层观点可能会使人们更好地理解大脑如何控制运动。
