8株克里米亚-刚果出血热病毒株的基因组序列草图
Draft Genome Sequences of Eight Crimean-Congo Hemorrhagic Fever Virus Strains.
作者信息
Koehler J W, Delp K L, Kearney B J, Conrad T A, Schoepp R J, Garrison A R, Altamura L A, Rossi C A, Minogue T D
机构信息
Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.
Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.
出版信息
Genome Announc. 2017 Jun 8;5(23):e00240-17. doi: 10.1128/genomeA.00240-17.
Abstract
Crimean-Congo hemorrhagic fever virus (CCHFV) is a geographically widespread RNA virus with a high degree of genomic diversity that complicates sequence-based diagnostics. Here, we sequenced eight CCHFV strains for improved assay design and deposition into FDA-ARGOS, the FDA's pathogen database for development and verification of next generation sequencing assays.
摘要
克里米亚-刚果出血热病毒（CCHFV）是一种在地理上广泛传播的RNA病毒，具有高度的基因组多样性，这使得基于序列的诊断变得复杂。在这里，我们对8株CCHFV毒株进行了测序，以改进检测方法的设计，并将其存入美国食品药品监督管理局（FDA）的ARGOS数据库，该数据库是FDA用于开发和验证下一代测序检测方法的病原体数据库。
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