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一种基于距离的实用干预措施对增加肺癌幸存者身体活动的可行性。

The feasibility of a pragmatic distance-based intervention to increase physical activity in lung cancer survivors.

作者信息

Peddle-McIntyre C J, Baker M K, Lee Y C G, Galvão D A, Cormie P, Graham V, Newton R U

机构信息

Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia.

School of Exercise Science, Australian Catholic University, Strathfield, NSW, Australia.

出版信息

Eur J Cancer Care (Engl). 2018 Jan;27(1). doi: 10.1111/ecc.12722. Epub 2017 Jun 9.

Abstract

The purpose of this study was to investigate the feasibility and preliminary efficacy of a pragmatic distance-based intervention designed to increase physical activity (PA) participation in lung cancer survivors. Fourteen lung cancer survivors were recruited via invitation from the State Cancer Registry to join a 12-week PA intervention of print materials paired with brief telephone follow-up. Outcome measures of feasibility, PA participation and quality of life (QoL) were assessed at baseline, post-intervention and follow-up via telephone interview. Eligibility, recruitment and attrition rates were 16%, 58% and 29% respectively. No adverse events were reported; however, pain scores worsened following the intervention (median change -3.6, IQR -8.0, 0.0). Average intervention adherence was 91% with low median ratings of participation burden (i.e., all items 1/7) and high trial evaluation (i.e., all items 7/7). Post-intervention, median change in self-reported moderate and vigorous PA was 84 min (IQR -22, 188), and several domains of QoL improved. However, for both of these outcomes, improvements were not maintained at follow-up. Our findings suggest that this pragmatic distance-based intervention was safe, had good adherence rates, and indicate potential for improving short-term PA and QoL in lung cancer survivors. Additional strategies are needed to improve other indicators of feasibility, particularly recruitment, retention and long-term maintenance of improvements. Australian New Zealand Clinical Trials Registration: ACTRN12612000085875.

摘要

本研究的目的是调查一种基于距离的实用干预措施的可行性和初步疗效,该干预措施旨在提高肺癌幸存者的身体活动(PA)参与度。通过州癌症登记处的邀请招募了14名肺癌幸存者,参加为期12周的PA干预,干预内容为印刷材料并辅以简短的电话随访。通过电话访谈在基线、干预后和随访时评估可行性、PA参与度和生活质量(QoL)等结果指标。符合条件率、招募率和失访率分别为16%、58%和29%。未报告不良事件;然而,干预后疼痛评分恶化(中位数变化-3.6,四分位间距-8.0,0.0)。平均干预依从性为91%,参与负担的中位数评分较低(即所有项目为1/7),试验评价较高(即所有项目为7/7)。干预后,自我报告的中等强度和剧烈PA的中位数变化为84分钟(四分位间距-22,188),QoL的几个领域有所改善。然而,对于这两个结果,随访时改善情况未得到维持。我们的研究结果表明,这种基于距离的实用干预措施是安全的,依从率良好,并显示出改善肺癌幸存者短期PA和QoL的潜力。需要额外的策略来改善可行性的其他指标,特别是招募、保留和改善的长期维持。澳大利亚新西兰临床试验注册:ACTRN12612000085875。

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