Singh N N, Millichamp C J
J Autism Dev Disord. 1985 Sep;15(3):257-67. doi: 10.1007/BF01531497.
Self-injury is a severe behavioral problem commonly observed in institutionalized mentally retarded individuals. While several forms of therapy are available, pharmacological treatment is most often used in institutions to control this behavior. This paper evaluated the clinical and experimental literature on the effects of pharmacotherapy for self-injury. Few general conclusions could be drawn mainly due to the small number of studies and the general lack of methodological rigor of these studies. However, there was some indication that antipsychotics and antimanics may prove to be useful in the treatment of self-injury and warrant further investigation. Several areas of future research were discussed.
自我伤害是在机构化的智力迟钝个体中常见的严重行为问题。虽然有几种治疗方法可供选择，但在机构中最常使用药物治疗来控制这种行为。本文评估了关于药物治疗自我伤害效果的临床和实验文献。由于研究数量少且这些研究普遍缺乏方法学严谨性，几乎无法得出一般性结论。然而，有迹象表明抗精神病药物和抗躁狂药物可能被证明对治疗自我伤害有用，值得进一步研究。文中还讨论了未来研究的几个领域。
