Bikic Aida, Christensen Torben Østergaard, Leckman James F, Bilenberg Niels, Dalsgaard Søren
a Department of Clinical Research , University of Southern Denmark , Odense , Denmark.
b Department for Child and Adolescent Psychiatry , Aabenraa , Denmark.
Nord J Psychiatry. 2017 Aug;71(6):455-464. doi: 10.1080/08039488.2017.1328070. Epub 2017 Jun 9.
The purpose of this trial was to examine the feasibility and efficacy of computerized cognitive exercises from Scientific Brain Training (SBT), compared to the computer game Tetris as an active placebo, in a pilot study of adolescents with attention-deficit/hyperactivity disorder (ADHD).
Eighteen adolescents with ADHD were randomized to treatment or control intervention for 7 weeks. Outcome measures were cognitive test, symptom, and motivation questionnaires.
SBT and Tetris were feasible as home-based interventions, and participants' compliance was high, but participants perceived both interventions as not very interesting or helpful. There were no significant group differences on cognitive and ADHD-symptom measures after intervention. Pre-post intra-group measurement showed that the SBT had a significant beneficial effect on sustained attention, while the active placebo had significant beneficial effects on working memory, both with large effect sizes.
Although no significant differences were found between groups on any measure, there were significant intra-group changes for each group.
在一项针对注意力缺陷多动障碍（ADHD）青少年的试点研究中，本试验旨在比较科学大脑训练（SBT）的计算机化认知训练与作为活性安慰剂的电脑游戏俄罗斯方块的可行性和有效性。
18名患有ADHD的青少年被随机分配接受为期7周的治疗或对照干预。结果测量包括认知测试、症状和动机问卷。
SBT和俄罗斯方块作为家庭干预措施是可行的，参与者的依从性很高，但参与者认为这两种干预措施都不是很有趣或有帮助。干预后，在认知和ADHD症状测量方面，两组之间没有显著差异。组内前后测量显示，SBT对持续注意力有显著的有益影响，而活性安慰剂对工作记忆有显著的有益影响，两者的效应量都很大。
尽管在任何测量指标上两组之间均未发现显著差异，但每组均有显著的组内变化。
