Department of Chemistry and Biochemistry, The University of Texas at Austin, 1 University Station, A1590, Austin, TX, USA.
Org Biomol Chem. 2011 Nov 7;9(21):7292-5. doi: 10.1039/c1ob06102j. Epub 2011 Sep 12.
The selective oxidation of thiols to disulfides and sulfides to sulfoxides using graphite oxide (GO), a heterogeneous carbocatalyst obtained from low cost, commercial starting materials is described. The aforementioned oxidation reactions were found to proceed rapidly (as short as 10 min in some cases) and in good yield (51-100%) (19 examples). No over-oxidation of the substrates was observed, and GO's heterogeneous nature facilitated isolation and purification of the target products.
本文描述了使用石墨氧化物（GO）作为非均相碳催化剂将硫醇选择性氧化为二硫化物、将硫化物氧化为亚砜。上述氧化反应进行得很快（在某些情况下短至 10 分钟），收率高（51-100%）（19 个实例）。未观察到底物过度氧化，GO 的非均相性质有利于目标产物的分离和纯化。
