Lunze Karsten, Lioznov Dmitry, Cheng Debbie M, Nikitin Ruslan V, Coleman Sharon M, Bridden Carly, Blokhina Elena, Krupitsky Evgeny, Samet Jeffrey H
Department of Medicine, Boston University School of Medicine, 801 Massachusetts Ave., CT 2079, Boston, MA, 02118, USA.
Section of General Internal Medicine, Boston Medical Center, Boston, MA, USA.
AIDS Behav. 2017 Sep;21(9):2609-2617. doi: 10.1007/s10461-017-1820-8.
Unhealthy alcohol use, highly prevalent in the Russian Federation (Russia), is associated with HIV risk behaviors among people living with HIV (PLWH). HIV stigma contributes to the HIV risk environment in Russia. To examine HIV stigma among Russian PLWH and to explore its association with unhealthy alcohol use, we conducted a longitudinal analysis of 700 PLWH in St. Petersburg, Russia. We assessed the association between alcohol dependence and HIV stigma measured at baseline and 12 months follow-up. Participants with alcohol dependence (n = 446) reported significantly higher HIV stigma scores over time than those without dependence (n = 254) (adjusted mean difference 0.60, 95% CI 0.03-1.17; p = 0.04). In secondary analyses, we examined recent risky alcohol use and did not detect an association with HIV stigma. Alcohol dependence is associated with high HIV stigma among Russian PLWH but the nature of the association is conjectural. HIV prevention efforts in Russia that address alcohol use disorders hold potential to mitigate HIV-related stigma and its possible adverse effects among PLWH.
不健康饮酒在俄罗斯联邦（俄罗斯）极为普遍，与艾滋病毒感染者（PLWH）的艾滋病毒风险行为相关。艾滋病毒污名化加剧了俄罗斯的艾滋病毒风险环境。为了调查俄罗斯艾滋病毒感染者中的艾滋病毒污名化情况，并探讨其与不健康饮酒的关联，我们对俄罗斯圣彼得堡的700名艾滋病毒感染者进行了纵向分析。我们评估了基线时和随访12个月时测量的酒精依赖与艾滋病毒污名化之间的关联。随着时间的推移，有酒精依赖的参与者（n = 446）报告的艾滋病毒污名化得分显著高于无酒精依赖的参与者（n = 254）（调整后平均差异为0.60，95%CI为0.03 - 1.17；p = 0.04）。在二次分析中，我们研究了近期的危险饮酒情况，未发现其与艾滋病毒污名化有关联。酒精依赖与俄罗斯艾滋病毒感染者中较高的艾滋病毒污名化相关，但这种关联的性质尚不确定。俄罗斯针对酒精使用障碍的艾滋病毒预防措施有可能减轻艾滋病毒感染者中与艾滋病毒相关的污名化及其可能产生的不利影响。
