Pawlikowski M, Stepien H, Kunert-Radek J, Schally A V
Biochem Biophys Res Commun. 1985 May 31;129(1):52-5. doi: 10.1016/0006-291x(85)91401-9.
The effect of somatostatin on the spontaneous proliferation of mouse spleen lymphocytes was investigated in vitro. The rate of 3H-thymidine incorporation was used as an index of lymphocyte proliferation. Somatostatin in a concentration of 10(-7) M enhanced the lymphocyte proliferation and abolished the antiproliferative effect of rat hypothalamic extract. Lower concentrations of somatostatin slightly decreased the lymphocyte DNA synthesis.
