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使用PTW-微金刚石进行未展平光子束的相对剂量测定。

Use of PTW-microDiamond for relative dosimetry of unflattened photon beams.

作者信息

Reggiori Giacomo, Stravato Antonella, Pimpinella Maria, Lobefalo Francesca, De Coste Vanessa, Fogliata Antonella, Mancosu Pietro, De Rose Fiorenza, Palumbo Valentina, Scorsetti Marta, Tomatis Stefano

机构信息

Physics Service of Radiation Oncology Dept., Humanitas Clinical and Research Hospital, Milan-Rozzano, Italy.

Physics Service of Radiation Oncology Dept., Humanitas Clinical and Research Hospital, Milan-Rozzano, Italy.

出版信息

Phys Med. 2017 Jun;38:45-53. doi: 10.1016/j.ejmp.2017.05.046. Epub 2017 May 10.

Abstract

PURPOSE

The increasing interest in SBRT treatments encourages the use of flattening filter free (FFF) beams. Aim of this work was to evaluate the performance of the PTW60019 microDiamond detector under 6MV and 10MVFFF beams delivered with the EDGE accelerator (Varian Medical System, Palo Alto, USA). A flattened 6MV beam was also considered for comparison.

METHODS

Short term stability, dose linearity and dose rate dependence were evaluated. Dose per pulse dependence was investigated in the range 0.2-2.2mGy/pulse. MicroDiamond profiles and output factors (OFs) were compared to those obtained with other detectors for field sizes ranging from 40×40cm to 0.6×0.6cm. In small fields, volume averaging effects were evaluated and the relevant correction factors were applied for each detector.

RESULTS

MicroDiamond short term stability, dose linearity and dependence on monitor unit rate were less than 0.8% for all energies. Response variations with dose per pulse were found within 1.8%. MicroDiamond output factors (OF) values differed from those measured with the reference ion-chamber for less than 1% up to 40×40cm fields where silicon diodes overestimate the dose of ≈3%. For small fields (<3×3cm) microDiamond and the unshielded silicon diode were in good agreement.

CONCLUSIONS

MicroDiamond showed optimal characteristics for relative dosimetry even under high dose rate beams. The effects due to dose per pulse dependence up to 2.2mGy/pulse are negligible. Compared to other detectors, microDiamond provides accurate OF measurements in the whole range of field sizes. For fields <1cm correction factors accounting for fluence perturbation and volume averaging could be required.

摘要

目的

对立体定向体部放疗(SBRT)治疗的兴趣日益增加,促使人们使用无均整器(FFF)射束。本研究的目的是评估PTW60019微型金刚石探测器在使用EDGE加速器(美国瓦里安医疗系统公司,帕洛阿尔托)提供的6MV和10MV FFF射束时的性能。还考虑了一个均整后的6MV射束用于比较。

方法

评估了短期稳定性、剂量线性和剂量率依赖性。研究了在0.2 - 2.2mGy/脉冲范围内的每脉冲剂量依赖性。将微型金刚石探测器的剂量分布和输出因子(OF)与其他探测器在40×40cm至0.6×0.6cm射野尺寸下获得的结果进行了比较。在小射野中,评估了体积平均效应,并为每个探测器应用了相关校正因子。

结果

对于所有能量,微型金刚石探测器的短期稳定性、剂量线性和对监测单位率的依赖性均小于0.8%。发现每脉冲剂量的响应变化在1.8%以内。在射野尺寸达40×40cm时,微型金刚石探测器的输出因子(OF)值与参考电离室测量值的差异小于1%,而硅二极管高估剂量约3%。对于小射野(<3×3cm),微型金刚石探测器与未加屏蔽的硅二极管结果吻合良好。

结论

即使在高剂量率射束下,微型金刚石探测器在相对剂量测量方面也表现出最佳特性。高达2.2mGy/脉冲的每脉冲剂量依赖性所产生的影响可忽略不计。与其他探测器相比,微型金刚石探测器在整个射野尺寸范围内都能提供准确的输出因子测量值。对于<1cm的射野,可能需要考虑注量扰动和体积平均的校正因子。

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