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6和15MV光子束小射野中Semiflex3D和微钻石在相对剂量学中的剂量学特性评估与比较

Evaluation and Comparison of Dosimetric Characteristics of Semiflex3D and Microdiamond in Relative Dosimetry under 6 and 15 MV Photon Beams in Small Fields.

作者信息

Momeni Harzanji Zahra, Larizadeh Mohammad Hassan, Namiranian Nasim, Nickfarjam Abolfazl

机构信息

MSc, Department of Medical Physics, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

MD, Department of Radiation Oncology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.

出版信息

J Biomed Phys Eng. 2022 Oct 1;12(5):477-488. doi: 10.31661/jbpe.v0i0.2008-1160. eCollection 2022 Oct.

Abstract

BACKGROUND

In modern radiotherapy techniques, the frequently small and non-uniformed fields can increase treatment efficiency due to their highly conformal dose distribution. Particular features including lack of Lateral Charge Particle Equilibrium (LCPE) lead to detectors with high resolution since any error in obtained dosimetric data could cause patient mistreatments.

OBJECTIVE

This study aims to evaluate and compare two small detectors (Semiflex3D and microdiamond) dosimetric characteristics in small field relative dosimetry.

MATERIAL AND METHODS

In this experimental study, the dosimetric properties of Semiflex3D and microdiamond were assessed under 6 and 15 MV photon beams. The linearity and stability of the detector's response and dose rate were measured. Square-field sizes ranging from 0.6×0.6 - 5×5 cm were used for obtaining percentage depth dose curves (PDDs) and in-plane profiles. The angular and temperature dependence of both detectors' responses were also studied.

RESULTS

The detector response shows good stability, no deviation from linearity, and low dose rate dependence (≤1.6%). PDDs and in-plan profiles of both detectors are in good agreement and no significant difference was observed except for the high dose gradient regions (-value≤0.017). Both detectors demonstrated low angular dependence (<0.3%) with temperature dependence lower than 1% for both detectors.

CONCLUSION

The results indicate both investigated detectors were well performed in small field relative dosimetry and for measuring penumbra, it is better to use microdiamond detector.

摘要

背景

在现代放射治疗技术中,由于其高度适形的剂量分布,频繁出现的小且不均匀的射野可提高治疗效率。包括缺乏横向带电粒子平衡(LCPE)在内的特殊特征导致需要高分辨率的探测器,因为所获得的剂量学数据中的任何误差都可能导致对患者的不当治疗。

目的

本研究旨在评估和比较两种小探测器(Semiflex3D和微钻石探测器)在小射野相对剂量学中的剂量学特性。

材料与方法

在本实验研究中,在6和15 MV光子束下评估Semiflex3D和微钻石探测器的剂量学特性。测量探测器响应和剂量率的线性度与稳定性。使用范围从0.6×0.6 - 5×5 cm的方形射野大小来获取百分深度剂量曲线(PDD)和平面内剂量分布曲线。还研究了两种探测器响应的角度和温度依赖性。

结果

探测器响应显示出良好的稳定性,无线性偏差,且剂量率依赖性低(≤1.6%)。两种探测器的PDD和平面内剂量分布曲线吻合良好,除了高剂量梯度区域(-值≤0.017)外未观察到显著差异。两种探测器均表现出低角度依赖性(<0.3%),且两种探测器的温度依赖性均低于1%。

结论

结果表明,两种被研究的探测器在小射野相对剂量学中表现良好,对于测量半值层,最好使用微钻石探测器。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c324/9589081/9989d1b794ae/JBPE-12-477-g001.jpg

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