Kluger Nicolas, Ranta Martta, Serlachius Martina
Department of Dermatology and Allergology, University of Helsinki, Espoo, Finland.
Department of Dermatology and Allergology, Helsinki University Central Hospital, Helsinki, Espoo, Finland.
Skin Appendage Disord. 2017 Mar;3(1):20-27. doi: 10.1159/000455236. Epub 2017 Jan 12.
Hidradenitis suppurativa (HS) is a chronic inflammatory disease that impacts the quality of life.
We evaluated its burden in a cohort of 26 Finnish patients in a single-center cross-sectional study. Demographic data, disease history, clinical data, treatment patterns, and workability were collected. Patients responded to the Dermatology Life Quality Index (DLQI) and Beck Depression Inventory (BDI-21).
Mean age of HS patients was 44.2 years and mean diagnostic delay was 13.7 years. Pain was rated the most bothersome symptom. Mean DLQI score was 8.31. Women consistently had higher scores than men for every item of the DLQI. Mean BDI-21 score was 10.69. Higher Hurley stage at visit ( = 0.001), female gender ( = 0.018), and higher BDI-21 score ( = 0.022) were variables that significantly affected the total DLQI score, whereas female gender ( = 0.004) was the only variable that significantly affected the total BDI-21 score using stepwise regression analysis.
The burden of HS is for the first time reported in Finland. The diagnostic delay is longer than previously reported and the results suggest that women are impacted by the disease more than men.
化脓性汗腺炎（HS）是一种影响生活质量的慢性炎症性疾病。
在一项单中心横断面研究中，我们评估了26名芬兰患者队列中的疾病负担。收集了人口统计学数据、疾病史、临床数据、治疗模式和工作能力等信息。患者对皮肤病生活质量指数（DLQI）和贝克抑郁量表（BDI - 21）进行了回应。
HS患者的平均年龄为44.2岁，平均诊断延迟为13.7年。疼痛被评为最困扰的症状。DLQI平均得分为8.31。在DLQI的每个项目中，女性得分始终高于男性。BDI - 21平均得分为10.69。就诊时更高的Hurley分期（= 0.001）、女性性别（= 0.018）和更高的BDI - 21得分（= 0.022）是显著影响DLQI总分的变量，而使用逐步回归分析时，女性性别（= 0.004）是显著影响BDI - 21总分的唯一变量。
芬兰首次报告了HS的疾病负担。诊断延迟比先前报告的更长，结果表明女性比男性受该疾病的影响更大。
