Gulati S, Misra A
Centre of Nutrition &Metabolic Research (C-NET), National Diabetes, Obesity and Cholesterol Foundation (N-DOC), SDA, New Delhi, India.
Diabetes Foundation (India), SDA, New Delhi, India.
Eur J Clin Nutr. 2017 Jul;71(7):850-857. doi: 10.1038/ejcn.2017.92. Epub 2017 Jun 14.
Obesity and type 2 diabetes are increasing in rural and urban regions of South Asia including India. Pattern of fat deposition in abdomen, ectopic fat deposition (liver, pancreas) and also low lean mass are contributory to early-onset insulin resistance, dysmetabolic state and diabetes in Asian Indians. These metabolic perturbations are further exacerbated by changing lifestyle, diet urbanization, and mechanization. Important dietary imbalances include increasing use of oils containing high amount of trans fatty acids and saturated fats (partially hydrogenated vegetable oil, palmolein oil) use of deep frying method and reheating of oils for cooking, high intake of saturated fats, sugar and refined carbohydrates, low intake of protein, fiber and increasing intake of processed foods. Although dietary intervention trials are few; the data show that improving quality of carbohydrates (more complex carbohydrates), improving fat quality (more monounsaturated fatty acids and omega 3 polyunsaturated fatty acids) and increasing protein intake could improve blood glucose, serum insulin, lipids, inflammatory markers and hepatic fat, but more studies are needed. Finally, regulatory framework must be tightened to impose taxes on sugar-sweetened beverages, oils such as palmolein, and dietary fats and limit trans fats.
在包括印度在内的南亚城乡地区,肥胖症和2型糖尿病的发病率正在上升。腹部脂肪沉积模式、异位脂肪沉积(肝脏、胰腺)以及低瘦体重是导致亚洲印度人早期胰岛素抵抗、代谢紊乱状态和糖尿病的因素。生活方式的改变、饮食城市化和机械化进一步加剧了这些代谢紊乱。重要的饮食失衡包括大量使用含有高量反式脂肪酸和饱和脂肪的油(部分氢化植物油、棕榈油)、使用油炸方法和反复加热食用油用于烹饪、饱和脂肪、糖和精制碳水化合物的高摄入量、蛋白质和纤维的低摄入量以及加工食品摄入量的增加。尽管饮食干预试验很少;但数据表明,改善碳水化合物质量(更多复杂碳水化合物)、改善脂肪质量(更多单不饱和脂肪酸和ω-3多不饱和脂肪酸)以及增加蛋白质摄入量可以改善血糖、血清胰岛素、血脂、炎症标志物和肝脏脂肪,但仍需要更多研究。最后,必须加强监管框架,对含糖饮料、棕榈油等油类以及膳食脂肪征税,并限制反式脂肪。