School of Social and Health Sciences, Leeds Trinity University, Durham, UK.
Tees Esk and Wear Valleys NHS Foundation Trust, Durham, UK.
Early Interv Psychiatry. 2019 Feb;13(1):47-52. doi: 10.1111/eip.12443. Epub 2017 Jun 14.
Evidence from meta-analyses of randomized clinical trials show interventions for young people at ultra-high risk (UHR) of developing psychosis are effective both clinically and economically. While research evidence has begun to be integrated into clinical guidelines, there is a lack of research on the implementation of these guidelines. This paper examines service provision for UHR individuals in accordance with current clinical guidelines within the National Health Service (NHS) in England.
A self-report online survey was completed by clinical leaders of early intervention in psychosis (EIP) teams (N = 50) within the NHS across England.
Of the 50 EIP teams responding (from 30 NHS trusts), 53% reported inclusion of the UHR group in their service mandate, with age range predominantly 14 to 35 years (81%) and service provided for at least 12 months (53%). Provision of services according to NICE clinical guidelines showed 50% of services offered cognitive behavioural therapy (CBT) for psychosis, and 42% offered family intervention. Contrary to guidelines, 50% of services offered antipsychotic medication. Around half of services provided training in assessment by Comprehensive Assessment of At Risk Mental States, psycho-education, CBT for psychosis, family work and treatment for anxiety and depression.
Despite clear evidence for the benefit of early intervention in this population, current provision for UHR within EIP services in England does not match clinical guidelines. While some argue this is due to a lack of allocated funding, it is important to note the similar variable adherence to clinical guidelines in the treatment of people with established schizophrenia.
来自随机临床试验荟萃分析的证据表明,针对有发展为精神病超高风险(UHR)的年轻人的干预措施在临床和经济上都有效。虽然研究证据已开始被纳入临床指南,但针对这些指南的实施情况的研究却很少。本文根据英国国民保健制度(NHS)中的当前临床指南,研究了为 UHR 个体提供的服务。
通过在线自我报告的方式,对英格兰 NHS 中的早期精神病干预(EIP)团队的临床负责人(N = 50)进行了调查。
在做出回应的 50 个 EIP 团队中(来自 30 个 NHS 信托),有 53%的团队报告说将 UHR 群体纳入其服务范围,年龄范围主要为 14 至 35 岁(81%),服务时间至少为 12 个月(53%)。根据 NICE 临床指南提供服务的情况表明,50%的服务提供针对精神病的认知行为疗法(CBT),42%的服务提供家庭干预。与指南相反,50%的服务提供抗精神病药物。大约一半的服务提供风险精神状态全面评估、心理教育、精神病 CBT、家庭工作以及焦虑和抑郁治疗方面的评估培训。
尽管有明确的证据表明早期干预对这一人群有益,但英格兰 EIP 服务中针对 UHR 的现行服务并未符合临床指南。虽然有人认为这是由于缺乏分配资金,但值得注意的是,在治疗已确诊的精神分裂症患者方面,对临床指南的遵守情况也存在类似的差异。