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用于检测动物和人类感染的血清学工具。

Serological tools for detection of infection in animals and humans.

作者信息

Yang Yong, Cai Ya Nan, Tong Ming Wei, Sun Na, Xuan Yin Hua, Kang Yan Jun, Vallée Isabelle, Boireau Pascal, Cheng Shi Peng, Liu Ming Yuan

机构信息

Wu xi Medical School, Jiang Nan University, Wu Xi 214122, Jiang su, China.

College of Animal Science and Technology, Jilin Agricultural University, Changchun, China.

出版信息

One Health. 2016 Mar 4;2:25-30. doi: 10.1016/j.onehlt.2015.11.005. eCollection 2016 Dec.

Abstract

Trichinellosis is a serious foodborne zoonotic disease. It is an important threat to public health in both developing and developed countries. Human infections are strongly associated with consuming undercooked meat containing infective larvae. The development of serological tools has enabled seroepidemiological studies and contributed to our knowledge on the importance of this parasite. Serological tests can also help the diagnosis of parasite infections in humans and the surveillance of animals. Generally speaking, serological techniques include detection methods for specific antibodies and for circulating parasite antigens in the serum or tissue fluids. Here, we present a comprehensive review of various methods used in the detection of antibodies against and circulating parasite antigens in animals and humans.

摘要

旋毛虫病是一种严重的食源性人畜共患病。它对发展中国家和发达国家的公共卫生都是一个重要威胁。人类感染与食用含有感染性幼虫的未煮熟肉类密切相关。血清学检测工具的发展推动了血清流行病学研究,并有助于我们了解这种寄生虫的重要性。血清学检测还可以帮助诊断人类的寄生虫感染以及动物监测。一般来说,血清学技术包括血清或组织液中特异性抗体和循环寄生虫抗原的检测方法。在此,我们对用于检测动物和人类中抗寄生虫抗体及循环寄生虫抗原的各种方法进行全面综述。

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