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类风湿关节炎中针对变形杆菌的抗体。

Antibodies to proteus in rheumatoid arthritis.

作者信息

Ebringer A, Ptaszynska T, Corbett M, Wilson C, Macafee Y, Avakian H, Baron P, James D C

出版信息

Lancet. 1985 Aug 10;2(8450):305-7. doi: 10.1016/s0140-6736(85)90352-6.

DOI:10.1016/s0140-6736(85)90352-6
PMID:2862470
Abstract

Antibodies to proteus species were measured in patients with rheumatoid arthritis (RA) and ankylosing spondylitis (AS) and in healthy controls by a Coombs agglutination method. The titres to Proteus mirabilis were higher in 30 RA patients being treated with gold than in 24 patients with active AS (p less than 0.001), 28 patients with inactive AS (p less than 0.001), and 41 healthy control subjects (p less than 0.001). Control studies with Klebsiella pneumoniae var oxytoca showed high antibody titres only in active AS patients.

摘要

采用库姆斯凝集法检测类风湿性关节炎(RA)和强直性脊柱炎(AS)患者以及健康对照者体内变形杆菌属抗体。30例接受金制剂治疗的RA患者体内奇异变形杆菌抗体滴度高于24例活动期AS患者(p<0.001)、28例非活动期AS患者(p<0.001)以及41例健康对照者(p<0.001)。用产酸克雷伯菌进行的对照研究显示,仅活动期AS患者体内抗体滴度较高。

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1
Antibodies to proteus in rheumatoid arthritis.类风湿关节炎中针对变形杆菌的抗体。
Lancet. 1985 Aug 10;2(8450):305-7. doi: 10.1016/s0140-6736(85)90352-6.
2
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Elevated levels of anti-proteus antibodies in patients with active rheumatoid arthritis.活动性类风湿关节炎患者中抗变形杆菌抗体水平升高。
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