农村老年人户外体育活动与健康的面板研究中空气污染对心肺的影响
Cardio-Respiratory Effects of Air Pollution in a Panel Study of Outdoor Physical Activity and Health in Rural Older Adults.
作者信息
Stieb David M, Shutt Robin, Kauri Lisa, Mason Sarah, Chen Li, Szyszkowicz Mieczyslaw, Dobbin Nina A, Rigden Marc, Jovic Branka, Mulholland Marie, Green Martin S, Liu Ling, Pelletier Guillaume, Weichenthal Scott A, Dales Robert E, Luginaah Isaac
机构信息
Population Studies Division, Health Canada (Dr Stieb, Dr Shutt, Dr Kauri, Dr Chen, Dr Szyszkowicz, Ms Jovic, Dr Liu, Dr Dales); School of Epidemiology, Public Health and Preventive Medicine University of Ottawa (Dr Stieb); Department of Geography, Western University (Ms Mason, Dr Luginaah); Air Health Science Division, Health Canada (Ms Dobbin, Dr Weichenthal); Hazard Identification Division, Health Canada (Mr Rigden, Dr Pelletier); University of Ottawa Heart Institute (Ms Mulholland, Dr Green); Environmental Epidemiology Research Group, McGill University (Dr Weichenthal); Department of Medicine, Ottawa Health Research Institute (Dr Dales), University of Ottawa, Canada.
出版信息
J Occup Environ Med. 2017 Apr;59(4):356-364. doi: 10.1097/JOM.0000000000000954.
OBJECTIVE
To examine cardio-respiratory effects of air pollution in rural older adults exercising outdoors.
METHODS
Adults 55 and over completed measurements of blood pressure, peak expiratory flow and oximetry daily, and of heart rate variability, endothelial function, spirometry, fraction of exhaled nitric oxide and urinary oxidative stress markers weekly, before and after outdoor exercise, for 10 weeks. Data were analyzed using linear mixed effect models.
RESULTS
Pooled estimates combining 2013 (n = 36 participants) and 2014 (n = 41) indicated that an interquartile increase in the air quality health index (AQHI) was associated with a significant (P < 0.05) increase in heart rate (2.1%) and significant decreases in high frequency power (-19.1%), root mean square of successive differences (-9.5%), and reactive hyperemia index (-6.5%).
CONCLUSIONS
We observed acute subclinical adverse effects of air pollution in rural older adults exercising outdoors.
目的
研究空气污染对在户外锻炼的农村老年人心肺功能的影响。
方法
55岁及以上的成年人在为期10周的户外锻炼前后，每天测量血压、呼气峰值流速和血氧饱和度，每周测量心率变异性、内皮功能、肺活量测定、呼出一氧化氮分数和尿氧化应激标志物。使用线性混合效应模型分析数据。
结果
综合2013年（36名参与者）和2014年（41名参与者）的数据估计表明，空气质量健康指数（AQHI）四分位数间距的增加与心率显著增加（2.1%，P<0.05）以及高频功率显著降低（-19.1%）、逐次差值均方根显著降低（-9.5%）和反应性充血指数显著降低（-6.5%）相关。
结论
我们观察到空气污染对在户外锻炼的农村老年人有急性亚临床不良反应。
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