用于更年期治疗的 ERAA：欢迎“设计雌激素”。
ERAAs for menopause treatment: Welcome the 'designer estrogens'.
机构信息
Assistant Professor, Clinical Internal Medicine, Division of General Internal Medicine, The Ohio State University, Columbus, OH, USA.
Center for Women's Health, The Ohio State University Wexner Medical Center, Upper Arlington, OH, USA.
出版信息
Cleve Clin J Med. 2017 Jun;84(6):463-470. doi: 10.3949/ccjm.84a.15140.
Estrogen receptor agonist-antagonists (ERAAs) selectively inhibit or stimulate estrogen-like action in targeted tissues. This review summarizes how ERAAs can be used in combination with an estrogen or alone to treat menopausal symptoms (vasomotor symptoms, genitourinary syndrome of menopause), breast cancer or the risk of breast cancer, osteopenia, osteoporosis, and other female midlife concerns.
雌激素受体激动剂拮抗剂（ERAAs）选择性地抑制或刺激靶向组织中的雌激素样作用。本综述总结了 ERAAs 如何与雌激素联合使用或单独使用来治疗绝经相关症状（血管舒缩症状、绝经后生殖泌尿系统综合征）、乳腺癌或乳腺癌风险、骨量减少症、骨质疏松症以及其他女性中年期相关问题。
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