Monich Patrícia R, Berti Fernanda V, Porto Luismar M, Henriques Bruno, Novaes de Oliveira Antonio P, Fredel Márcio C, Souza Júlio C M
Ceramic and Composite Materials Research Laboratories (CERMAT), Federal University of Santa Catarina (UFSC), Florianópolis/SC 88040-900, Brazil.
Integrated Technologies Laboratory (InteLAB), Federal University of Santa Catarina (UFSC), Florianópolis/SC 88040-900, Brazil.
Mater Sci Eng C Mater Biol Appl. 2017 Oct 1;79:354-362. doi: 10.1016/j.msec.2017.05.031. Epub 2017 May 8.
The main aim of this study was to assess the physicochemical and biological properties of a novel poly(ether ether ketone) (PEEK) composite containing 30%wt natural amorphous silica fibers (NASF). PEEK and NASF powders were previously functionalized by atomization and citric acid in order to enhance adhesion between polymeric matrix and fillers. Then, composites were produced by cold compression molding technique at 350°C for 3h. Materials were characterized by chemical, microstructural, thermophysical, mechanical and cytotoxic analysis. The results of the mechanical assays showed that the incorporation fibers increased the elastic modulus of the resultant PEEK composite in 56% while its microhardness increased in 26.7%. Chemical and microscopic analyses detected a good interfacial adhesion between PEEK and NASF. The results of the cytotoxicity assays indicated that PEEK/NASF composites stimulated the metabolic activity of fibroblasts and therefore a high cytocompatibility was noticed. PEEK composites embedding natural amorphous silica fibers revealed a high potential to be used in medicine and dentistry replacing several polymeric and composite materials.
本研究的主要目的是评估一种新型的含有30%重量比天然无定形二氧化硅纤维（NASF）的聚醚醚酮（PEEK）复合材料的物理化学和生物学特性。PEEK和NASF粉末先前通过雾化和柠檬酸进行了功能化处理，以增强聚合物基体与填料之间的附着力。然后，通过冷压成型技术在350°C下制备复合材料3小时。通过化学、微观结构、热物理、力学和细胞毒性分析对材料进行了表征。力学测试结果表明，纤维的加入使所得PEEK复合材料的弹性模量提高了56%，而其显微硬度提高了26.7%。化学和微观分析检测到PEEK与NASF之间有良好的界面附着力。细胞毒性试验结果表明，PEEK/NASF复合材料刺激了成纤维细胞的代谢活性，因此具有较高的细胞相容性。嵌入天然无定形二氧化硅纤维的PEEK复合材料显示出在医学和牙科领域替代多种聚合物和复合材料的巨大潜力。
