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作为神经体液整合模型的穹窿下器

The subfornical organ as a model of neurohumoral integration.

作者信息

Gross P M

出版信息

Brain Res Bull. 1985 Jul;15(1):65-70. doi: 10.1016/0361-9230(85)90062-0.

DOI:10.1016/0361-9230(85)90062-0
PMID:2862971
Abstract

Through its specialized morphology, sensitivity to angiotensin II, and strategic anatomical connections, the subfornical organ is intimately involved in the translation of peripheral thirst to behavioral and physiological actions for establishing body fluid homeostasis. Evidence identifying the subfornical organ as a "neuroendocrine transducer" is summarized in categories based on its structure-function relationships with systemic blood, cerebrospinal fluid, and its afferent and efferent neural connections.

摘要

通过其特殊的形态、对血管紧张素II的敏感性以及关键的解剖学联系,穹窿下器密切参与将外周口渴转化为行为和生理反应,以建立体液平衡。基于其与全身血液、脑脊液及其传入和传出神经联系的结构-功能关系,将确定穹窿下器为“神经内分泌转换器”的证据进行了分类总结。

相似文献

1
The subfornical organ as a model of neurohumoral integration.作为神经体液整合模型的穹窿下器
Brain Res Bull. 1985 Jul;15(1):65-70. doi: 10.1016/0361-9230(85)90062-0.
2
The periventricular anteroventral third ventricle (AV3V): its relationship with the subfornical organ and neural systems involved in maintaining body fluid homeostasis.脑室周围前腹侧第三脑室(AV3V):它与穹窿下器以及参与维持体液平衡的神经系统的关系。
Brain Res Bull. 1985 Dec;15(6):595-601. doi: 10.1016/0361-9230(85)90209-6.
3
Anatomical evidence that neural circuits related to the subfornical organ contain angiotensin II.与穹窿下器官相关的神经回路含有血管紧张素II的解剖学证据。
Brain Res Bull. 1985 Jul;15(1):79-82. doi: 10.1016/0361-9230(85)90064-4.
4
Neural projections subserving the initiation of a specific motivated behavior in the rat: new projections from the subfornical organ.
Brain Res. 1986 Aug 6;379(2):399-403. doi: 10.1016/0006-8993(86)90799-7.
5
Sensory circumventricular organs and brain homeostatic pathways.感觉性室周器官与脑内稳态通路。
FASEB J. 1993 May;7(8):678-86. doi: 10.1096/fasebj.7.8.8500693.
6
Electrophysiology of the subfornical organ and its hypothalamic connections--an in-vivo study in the rat.穹窿下器的电生理学及其与下丘脑的联系——大鼠体内研究
Brain Res Bull. 1985 Jul;15(1):83-6. doi: 10.1016/0361-9230(85)90065-6.
7
Subfornical organ efferents to neural systems for control of body water.穹窿下器向控制机体水液的神经系统发出的传出纤维。
Science. 1979 Sep 7;205(4410):1022-5. doi: 10.1126/science.472723.
8
[The subfornical organ today: morphological aspects and functional role].[今日的穹窿下器官:形态学方面及功能作用]
Arch Ital Anat Embriol. 1989 Jan-Mar;94(1):1-53.
9
Integration between the lateral preoptic area and subfornical organ in the regulation of water intake and hemodynamics in the rat.大鼠视前外侧区与穹窿下器在水摄入和血流动力学调节中的整合作用
Braz J Med Biol Res. 1987;20(3-4):369-81.
10
The subfornical organ and the integration of multiple factors in thirst.穹窿下器与口渴中多种因素的整合
Physiol Behav. 1984 Jan;32(1):69-74. doi: 10.1016/0031-9384(84)90072-6.

引用本文的文献

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Expression of prokineticins and their receptors in the adult mouse brain.促动力蛋白及其受体在成年小鼠大脑中的表达。
J Comp Neurol. 2006 Oct 20;498(6):796-809. doi: 10.1002/cne.21087.
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Receptor autoradiographic analysis of insulin-like growth factor-I (IGF-I) binding sites in rat forebrain and pituitary gland.大鼠前脑和垂体中胰岛素样生长因子-I(IGF-I)结合位点的受体放射自显影分析。
Cell Mol Neurobiol. 1989 Sep;9(3):357-67. doi: 10.1007/BF00711415.
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Expression of basic fibroblast growth factor and its receptor in the rat subfornical organ.
碱性成纤维细胞生长因子及其受体在大鼠穹窿下器中的表达
Neuroendocrinology. 1991 Jul;54(1):55-61. doi: 10.1159/000125851.