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Amplification of the c-myc oncogene in human plasma-cell leukemia.

作者信息

Sümegi J, Hedberg T, Björkholm M, Godal T, Mellstedt H, Nilsson M G, Perlman C, Klein G

出版信息

Int J Cancer. 1985 Sep 15;36(3):367-71.

PMID:2863225
Abstract

We have examined primary leukemia cells from multiple myeloma and plasma-cell leukemia patients for rearrangement, amplification and expression of c-myc oncogene. No rearrangement or detectable amplification of the c-myc could be found in 21 cases of multiple myeloma. In contrast, 2/3 cases of plasma-cell leukemia showed amplification of the oncogene with concomitant higher level of expression.

摘要

相似文献

1
Amplification of the c-myc oncogene in human plasma-cell leukemia.
Int J Cancer. 1985 Sep 15;36(3):367-71.
2
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引用本文的文献

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Plasma cell leukemia: consensus statement on diagnostic requirements, response criteria and treatment recommendations by the International Myeloma Working Group.浆细胞白血病：国际骨髓瘤工作组关于诊断要求、反应标准和治疗建议的共识声明。
Leukemia. 2013 Apr;27(4):780-91. doi: 10.1038/leu.2012.336. Epub 2012 Nov 21.
2
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Blood. 2012 Sep 20;120(12):2376-89. doi: 10.1182/blood-2012-05-408682. Epub 2012 Jul 26.
3
A single nucleotide change in the c-myc internal ribosome entry segment leads to enhanced binding of a group of protein factors.
c-myc内部核糖体进入片段中的单个核苷酸变化导致一组蛋白质因子的结合增强。
Nucleic Acids Res. 1998 Jul 1;26(13):3097-103. doi: 10.1093/nar/26.13.3097.
4
Multiple myeloma: increasing evidence for a multistep transformation process.多发性骨髓瘤：多步骤转化过程的证据日益增多。
Blood. 1998 Jan 1;91(1):3-21.
5
Immunoglobulin gene sequence analysis to further assess B-cell origin of multiple myeloma.免疫球蛋白基因序列分析以进一步评估多发性骨髓瘤的B细胞起源。
Clin Diagn Lab Immunol. 1995 Jan;2(1):44-52. doi: 10.1128/cdli.2.1.44-52.1995.
6
Complex translocation disrupts c-myc regulation in a human plasma cell myeloma.复杂易位破坏人类浆细胞骨髓瘤中的c-myc调控。
Mol Cell Biol. 1988 Jan;8(1):124-9. doi: 10.1128/mcb.8.1.124-129.1988.
7
Consistent chromosome 3p deletion and loss of heterozygosity in renal cell carcinoma.肾细胞癌中一致的3号染色体短臂缺失和杂合性缺失
Proc Natl Acad Sci U S A. 1988 Mar;85(5):1571-5. doi: 10.1073/pnas.85.5.1571.
8
Structure and expression of B-myc, a new member of the myc gene family.myc基因家族新成员B-myc的结构与表达
Mol Cell Biol. 1988 Aug;8(8):3168-74. doi: 10.1128/mcb.8.8.3168-3174.1988.
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An E mu-v-abl transgene elicits plasmacytomas in concert with an activated myc gene.一个Eμ-v-abl转基因与激活的myc基因共同引发浆细胞瘤。
EMBO J. 1990 Mar;9(3):897-905. doi: 10.1002/j.1460-2075.1990.tb08187.x.