对大肠杆菌中pepN基因体内表达的多种调控：pepN - lacZ操纵子和蛋白质融合菌株的研究
Multiple controls exerted on in vivo expression of the pepN gene in Escherichia coli: studies with pepN-lacZ operon and protein fusion strains.
作者信息
Gharbi S, Belaich A, Murgier M, Lazdunski A
出版信息
J Bacteriol. 1985 Sep;163(3):1191-5. doi: 10.1128/jb.163.3.1191-1195.1985.
Abstract
Three physiological conditions were shown to promote transcriptional regulation of pepN expression: phosphate limitation, the nature of the source of carbon and energy, and anaerobiosis. The transcriptional level of regulation can be deduced from the observation of these effects in strains carrying operon fusion pepN-lacZ. Mutations in the various genes phoB, phoM, phoR, crp, and fnr (oxrA) did not affect pepN expression.
摘要
研究表明，三种生理条件可促进pepN表达的转录调控：磷酸盐限制、碳源和能源的性质以及厌氧状态。调控的转录水平可通过观察携带操纵子融合pepN-lacZ的菌株中的这些效应来推断。phoB、phoM、phoR、crp和fnr（oxrA）等各种基因的突变并不影响pepN的表达。
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