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自闭症谱系障碍儿童在探索早期发育研究中的自伤行为。

Self-injurious behaviors in children with autism spectrum disorder enrolled in the Study to Explore Early Development.

机构信息

1 University of Colorado Denver, USA.

2 Centers for Disease Control and Prevention, USA.

出版信息

Autism. 2018 Jul;22(5):625-635. doi: 10.1177/1362361316689330. Epub 2017 Jun 21.

Abstract

We assessed potential factors associated with "current" or "ever" self-injurious behaviors, reported in the Autism Diagnostic Interview-Revised, among children with autism spectrum disorder (n = 692) from the Study to Explore Early Development. Data on factors examined were obtained from questionnaires, standardized clinical instruments, and birth certificates. We employed a log-binomial regression to assess these associations. Although most associations were quite similar for currently and ever exhibiting self-injurious behaviors, a few differences were noted. We documented previously unreported associations of current self-injurious behaviors with maternal age and cesarean delivery, and ever self-injurious behaviors with maternal age, child sex, gestational age, and maternal race. We also confirmed previously reported associations with adaptive skills, somatic conditions (sleep, gastrointestinal, and sensory abnormalities), and other behavioral problems. These findings are informative for clinical practice and future research.

摘要

我们评估了与自闭症谱系障碍儿童(n=692)的《自闭症诊断访谈修订版》中报告的“当前”或“曾经”自伤行为相关的潜在因素,这些儿童来自早期发展研究。从调查问卷、标准化临床工具和出生证明中获取了检查因素的数据。我们采用对数二项式回归来评估这些关联。尽管当前和曾经表现出自伤行为的大多数关联非常相似,但也注意到了一些差异。我们记录了当前自伤行为与母亲年龄和剖腹产、曾经自伤行为与母亲年龄、儿童性别、胎龄和母亲种族之间以前未报告的关联。我们还证实了与适应技能、躯体状况(睡眠、胃肠道和感觉异常)和其他行为问题的先前报告关联。这些发现对临床实践和未来的研究很有意义。

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