a Faculty of Physical Education and Recreation , University of Alberta , Edmonton , Canada.
b Department of Oncology , University of Alberta, Cross Cancer Institute , Edmonton , Canada.
Psychol Health Med. 2018 Feb;23(2):224-231. doi: 10.1080/13548506.2017.1344356. Epub 2017 Jun 21.
This pilot study explored predictors of adherence to exercise during and after neoadjuvant chemoradiotherapy (NACRT) in rectal cancer patients. Eighteen rectal cancer patients were prescribed three supervised aerobic exercise sessions/week during NACRT followed by ≥150 min/week of unsupervised aerobic exercise after NACRT. Although not statistically significant, adherence to supervised exercise during NACRT was meaningfully better for patients who were women (d = .82; P = .12), younger (d = -.62; P = .30), married (d = .62; P = .42), with better mental health (r = .32; P = .21), fewer diarrhea symptoms (r = .48; P = .052), and higher anticipated enjoyment (r = .31; P = .23), support (r = .32; P = .22), and motivation (r = .31; P = .23). After NACRT, adherence was significantly better for patients who reported worse mental health (r = -.56; P = .046) and meaningfully better for patients who were women (d = .54; P = .38), better educated (d = .77; P = .22), had no comorbidities (d = -.63; P = .17), and exercised at baseline (d = 1.05; P = .12). Demographics, tumor side effects, and motivational variables may predict adherence to exercise during and after NACRT.
这项初步研究旨在探讨直肠癌患者在新辅助放化疗（NACRT）期间和之后坚持锻炼的预测因素。18 名直肠癌患者在 NACRT 期间被规定每周进行 3 次监督性有氧运动，NACRT 后每周进行≥150 分钟的非监督性有氧运动。尽管没有统计学意义，但对于女性（d=0.82；P=0.12）、年轻（d=-0.62；P=0.30）、已婚（d=0.62；P=0.42）、心理健康状况较好（r=0.32；P=0.21）、腹泻症状较少（r=0.48；P=0.052）、预期享受度较高（r=0.31；P=0.23）、支持度较高（r=0.32；P=0.22）和动机度较高（r=0.31；P=0.23）的患者，其 NACRT 期间监督性锻炼的依从性有显著提高。NACRT 后，心理健康状况较差的患者（r=-0.56；P=0.046）、女性（d=-0.54；P=0.38）、教育程度较高（d=0.77；P=0.22）、无合并症（d=-0.63；P=0.17）和基线运动（d=1.05；P=0.12）的患者，其依从性显著提高。人口统计学、肿瘤副作用和动机变量可能预测 NACRT 期间和之后的锻炼依从性。
