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生物信息学:不可或缺,却又显而易见?

Bioinformatics: indispensable, yet hidden in plain sight?

作者信息

Bartlett Andrew, Penders Bart, Lewis Jamie

机构信息

Department of Sociological Studies, University of Sheffield, Elmfield, Northumberland Road, Sheffield, S10 2TU, UK.

Department of Health, Ethics & Society, Care and Public Health Research Institute (Caphri), Maastricht University, PO Box 616, Maastricht, 6200MD, the Netherlands.

出版信息

BMC Bioinformatics. 2017 Jun 21;18(1):311. doi: 10.1186/s12859-017-1730-9.

Abstract

BACKGROUND

Bioinformatics has multitudinous identities, organisational alignments and disciplinary links. This variety allows bioinformaticians and bioinformatic work to contribute to much (if not most) of life science research in profound ways. The multitude of bioinformatic work also translates into a multitude of credit-distribution arrangements, apparently dismissing that work.

RESULTS

We report on the epistemic and social arrangements that characterise the relationship between bioinformatics and life science. We describe, in sociological terms, the character, power and future of bioinformatic work. The character of bioinformatic work is such that its cultural, institutional and technical structures allow for it to be black-boxed easily. The result is that bioinformatic expertise and contributions travel easily and quickly, yet remain largely uncredited. The power of bioinformatic work is shaped by its dependency on life science work, which combined with the black-boxed character of bioinformatic expertise further contributes to situating bioinformatics on the periphery of the life sciences. Finally, the imagined futures of bioinformatic work suggest that bioinformatics will become ever more indispensable without necessarily becoming more visible, forcing bioinformaticians into difficult professional and career choices.

CONCLUSIONS

Bioinformatic expertise and labour is epistemically central but often institutionally peripheral. In part, this is a result of the ways in which the character, power distribution and potential futures of bioinformatics are constituted. However, alternative paths can be imagined.

摘要

背景

生物信息学具有众多的身份、组织关联和学科联系。这种多样性使得生物信息学家和生物信息学工作能够以深远的方式为大部分(如果不是绝大部分)生命科学研究做出贡献。大量的生物信息学工作也转化为众多的学分分配安排,这显然忽视了这项工作。

结果

我们报告了表征生物信息学与生命科学之间关系的认知和社会安排。我们从社会学角度描述了生物信息学工作的特点、影响力和未来。生物信息学工作的特点在于其文化、制度和技术结构使其很容易被黑箱化。结果是,生物信息学专业知识和贡献能够轻松快速地传播,但在很大程度上仍未得到认可。生物信息学工作的影响力受到其对生命科学工作的依赖的影响,这与生物信息学专业知识的黑箱化特点相结合,进一步导致生物信息学处于生命科学的边缘地位。最后,对生物信息学工作未来的设想表明,生物信息学将变得越来越不可或缺,但不一定会变得更加引人注目,这迫使生物信息学家面临艰难的职业选择。

结论

生物信息学专业知识和劳动力在认知上处于核心地位,但在制度上往往处于边缘地位。部分原因在于生物信息学的特点、权力分配和潜在未来的构成方式。然而,可以设想其他途径。

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