Natekar Madhukar, Raghuveer Hosahallli-Puttaiah, Rayapati Dilip-Kumar, Shobha Eshwara-Singh, Prashanth Nagesh-Tavane, Rangan Vinod, Panicker Archana G
Post Graduate Student , Department of Oral and Maxillofacial Surgery, Dayananda Sagar College of Dental Sciences.
MDS, Principal and Head of Department of Oral and Maxillofacial Surgery, Dayananda Sagar College of Dental Sciences.
J Clin Exp Dent. 2017 Jun 1;9(6):e779-e784. doi: 10.4317/jced.53602. eCollection 2017 Jun.
The comparatively evaluate the three surgical treatment modalities namely cryosurgery, diode and CO2 laser surgery in terms of healing outcomes on the day of surgery, first and second week post operatively and recurrence at the end of 18 months was assessed.
Thirty selected patients were divided randomly into three groups. Each group comprising of ten patients were subjected to one of the three modalities of treatment namely cryosurgery, diode laser or CO2 laser surgery for ablation of OL. Obtained data was analyzed using mainly using Chi-square and Anova tests.
Study showed statistical significant differences (p > 0.05) for evaluation parameters like pain, edema and scar. The parameters like infection, recurrence, bleeding showed no statistical significance. Pain was significantly higher in CO2 laser surgery group as compared with diode laser group. There was no recurrence observed at the end of the 6 months follow up period in all the three study groups.
Observations from the study highlights that all three surgical modalities used in this study were effective for treatment of OL, and the overall summation of the results of the study showed that laser therapy (CO2 and Diode) seems to offer better clinically significant results than cryotherapy. Oral premalignant lesion, leukoplakia, cryosurgery, CO2 laser surgery, diode laser surgery.
对冷冻手术、二极管激光手术和二氧化碳激光手术这三种手术治疗方式在手术当天、术后第一周和第二周的愈合结果以及18个月结束时的复发情况进行比较评估。
选取30例患者随机分为三组。每组10例患者分别接受冷冻手术、二极管激光手术或二氧化碳激光手术这三种治疗方式之一进行口腔白斑消融。主要使用卡方检验和方差分析对获得的数据进行分析。
研究显示，在疼痛、水肿和瘢痕等评估参数方面存在统计学显著差异（p>0.05）。感染、复发、出血等参数无统计学意义。与二极管激光手术组相比，二氧化碳激光手术组的疼痛明显更高。在所有三个研究组的6个月随访期结束时均未观察到复发。
该研究的观察结果表明，本研究中使用的所有三种手术方式对口腔白斑的治疗均有效，研究结果的总体总结表明，激光治疗（二氧化碳激光和二极管激光）似乎比冷冻治疗提供更好的临床显著效果。口腔癌前病变、白斑、冷冻手术、二氧化碳激光手术、二极管激光手术。
