Jankowska Danuta, Palabindala Venkataraman, Salim Sohail Abdul
Department of Internal Medicine, Brookdale Hospital Medical Center, Brooklyn, NY, USA.
Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
J Community Hosp Intern Med Perspect. 2017 Jun 6;7(2):130-133. doi: 10.1080/20009666.2017.1324236. eCollection 2017 Mar.
Carbon monoxide poisoning has been documented in literature to cause severe neurological and tissue toxicity within the body. However, cardiotoxicity is often overlooked, but not uncommon. Previous research studies and case reports have revealed a significant relationship between carbon monoxide intoxication and myocardial ischemic events. We report a case of a 48-year-old male, who was exposed to severe smoke inhalation due to a house fire and subsequently developed a non-ST elevation myocardial infarction. Ischemic changes were evident on electrocardiogram, which demonstrated T-wave inversion in lead III and ST-segment depression in leads V4-V6. Elevated cardiac enzymes were also present. After standard treatment for an acute cardiac event, the patient fully recovered. This case demonstrates that myocardial ischemic changes due to carbon monoxide poisoning may be reversible if recognized in early stages and treated appropriately, thus reminding physicians that a proper cardiovascular examination and diagnostic testing should be performed on all patients with carbon monoxide poisoning. : NSTEMI: Non-ST elevation myocardial infarction.
文献记载,一氧化碳中毒会在体内引发严重的神经毒性和组织毒性。然而,心脏毒性常常被忽视,但并非罕见。以往的研究和病例报告显示,一氧化碳中毒与心肌缺血事件之间存在显著关联。我们报告一例48岁男性病例,该患者因房屋火灾吸入大量浓烟,随后发生非ST段抬高型心肌梗死。心电图显示缺血性改变,Ⅲ导联T波倒置,V4 - V6导联ST段压低。心肌酶也升高。经过急性心脏事件的标准治疗后,患者完全康复。该病例表明,如果在早期阶段识别并进行适当治疗,一氧化碳中毒导致的心肌缺血改变可能是可逆的,从而提醒医生应对所有一氧化碳中毒患者进行适当的心血管检查和诊断测试。:NSTEMI:非ST段抬高型心肌梗死