Fitzpatrick Elizabeth M, Al-Essa Rakan S, Whittingham JoAnne, Fitzpatrick Jessica
a Faculty of Health Sciences , University of Ottawa , Ottawa , Canada.
b Children's Hospital of Eastern Ontario Research Institute , Ottawa , Canada.
Int J Audiol. 2017 Nov;56(11):819-828. doi: 10.1080/14992027.2017.1337938. Epub 2017 Jun 22.
The purpose of this study was to describe the clinical characteristics of children with unilateral hearing loss (UHL), examine deterioration in hearing, and explore amplification decisions.
Population-based data were collected prospectively from time of diagnosis. Serial audiograms and amplification details were retrospectively extracted from clinical charts to document the trajectory and management of hearing loss.
The study included all children identified with UHL in one region of Canada over a 13-year period (2003-2015) after implementation of universal newborn hearing screening.
Of 537 children with permanent hearing loss, 20.1% (108) presented with UHL at diagnosis. They were identified at a median age of 13.9 months (IQR: 2.8, 49.0). Children with congenital loss were identified at 2.8 months (IQR: 2.0, 3.6) and made up 47.2% (n = 51), reflecting that a substantial portion had late-onset, acquired or late-identified loss. A total of 42.4% (n = 39) showed deterioration in hearing, including 16 (17.4%) who developed bilateral loss. By study end, 73.1% (79/108) of children had received amplification recommendations.
Up to 20% of children with permanent HL are first diagnosed with UHL. About 40% are at risk for deterioration in hearing either in the impaired ear and/or in the normal hearing ear.
本研究旨在描述单侧听力损失（UHL）儿童的临床特征，检查听力恶化情况，并探讨听力放大决策。
从诊断时开始前瞻性收集基于人群的数据。回顾性地从临床图表中提取系列听力图和听力放大细节，以记录听力损失的发展轨迹和管理情况。
该研究纳入了加拿大一个地区在实施普遍新生儿听力筛查后的13年期间（2003 - 2015年）所有确诊为UHL的儿童。
在537例永久性听力损失儿童中，20.1%（108例）在诊断时表现为UHL。他们的确诊中位年龄为13.9个月（四分位间距：2.8，49.0）。先天性听力损失儿童在2.8个月时确诊（四分位间距：2.0，3.6），占47.2%（n = 51），这表明相当一部分儿童为迟发性、获得性或迟发性确诊的听力损失。共有42.4%（n = 39）的儿童听力出现恶化，其中16例（17.4%）发展为双侧听力损失。到研究结束时，73.1%（79/108）的儿童已收到听力放大建议。
高达20%的永久性听力损失儿童最初被诊断为UHL。约40%的儿童在患侧耳和/或健侧耳有听力恶化的风险。
