Computer Science Department, University of Quebec at Chicoutimi, Chicoutimi, QC G7H 2B1, Canada.
Computer Science Department, University of Quebec at Montreal, Montreal, QC H2L 2C4, Canada.
Sensors (Basel). 2017 Jun 23;17(7):1486. doi: 10.3390/s17071486.
In the last three decades, researchers have examined extensively how context-aware systems can assist people, specifically those suffering from incurable diseases, to help them cope with their medical illness. Over the years, a huge number of studies on Chronic Obstructive Pulmonary Disease (COPD) have been published. However, how to derive relevant attributes and early detection of COPD exacerbations remains a challenge. In this research work, we will use an efficient algorithm to select relevant attributes where there is no proper approach in this domain. Such algorithm predicts exacerbations with high accuracy by adding discretization process, and organizes the pertinent attributes in priority order based on their impact to facilitate the emergency medical treatment. In this paper, we propose an extension of our existing Helper Context-Aware Engine System (HCES) for COPD. This project uses Bayesian network algorithm to depict the dependency between the COPD symptoms (attributes) in order to overcome the insufficiency and the independency hypothesis of naïve Bayesian. In addition, the dependency in Bayesian network is realized using TAN algorithm rather than consulting pneumologists. All these combined algorithms (discretization, selection, dependency, and the ordering of the relevant attributes) constitute an effective prediction model, comparing to effective ones. Moreover, an investigation and comparison of different scenarios of these algorithms are also done to verify which sequence of steps of prediction model gives more accurate results. Finally, we designed and validated a computer-aided support application to integrate different steps of this model. The findings of our system HCES has shown promising results using Area Under Receiver Operating Characteristic (AUC = 81.5%).
在过去的三十年中,研究人员广泛研究了上下文感知系统如何帮助人们,特别是那些患有不治之症的人,帮助他们应对疾病。多年来,发表了大量关于慢性阻塞性肺疾病(COPD)的研究。然而,如何得出相关属性并早期检测 COPD 恶化仍然是一个挑战。在这项研究工作中,我们将使用一种有效的算法来选择相关属性,而在该领域没有适当的方法。该算法通过添加离散化过程来准确预测恶化,并根据其对紧急医疗的影响对相关属性进行优先级排序。在本文中,我们提出了对现有的 Helper Context-Aware Engine System (HCES) 的扩展,用于 COPD。该项目使用贝叶斯网络算法来描述 COPD 症状(属性)之间的依赖关系,以克服朴素贝叶斯的不足和独立性假设。此外,贝叶斯网络中的依赖关系是使用 TAN 算法实现的,而不是咨询肺病专家。所有这些组合算法(离散化、选择、依赖关系和相关属性的排序)构成了一个有效的预测模型,与有效的模型相比。此外,还对这些算法的不同场景进行了调查和比较,以验证预测模型的哪个步骤序列能给出更准确的结果。最后,我们设计并验证了一个计算机辅助支持应用程序,以整合该模型的不同步骤。我们的系统 HCES 的发现使用接收器工作特征曲线下面积(AUC = 81.5%)显示出了有希望的结果。