性别对真实队列中 COPD 表达的影响。
Impact of gender on COPD expression in a real-life cohort.
机构信息
Service de Pneumologie et Soins Intensifs Respiratoires, Groupe Hospitalier Cochin Broca Hôtel-Dieu, AP-HP and Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
出版信息
Respir Res. 2014 Feb 17;15(1):20. doi: 10.1186/1465-9921-15-20.
Abstract
Reports regarding gender-related differences in COPD expression have provided conflicting results. In the French Initiatives BPCO real-world cohort, which contained 688 patients (146 women) when data were extracted, women were matched with men (1:3 ratio: n = 107:275) on age (5-year intervals) and FEV1 (5% predicted intervals) and comparisons were performed using univariate logistic regressions. For a given age and level of airflow obstruction, women with COPD had higher BOD scores due to more pronounced dyspnea and lower BMI, suggesting worse prognosis, and were more likely to exhibit anxiety, suggesting the need for specific assessment and care.
摘要
关于 COPD 表达中的性别差异的报告提供了相互矛盾的结果。在提取数据时包含 688 名患者（146 名女性）的法国 COPD 真实世界队列倡议中，女性按照年龄（每 5 年为一个区间）和 FEV1（预测值的每 5%为一个区间）与男性进行匹配（1:3 比例：n=107:275），并使用单变量逻辑回归进行比较。对于给定的年龄和气流阻塞程度，COPD 女性由于更明显的呼吸困难和较低的 BMI，导致 BOD 评分更高，表明预后更差，并且更有可能出现焦虑，这表明需要进行特定的评估和护理。
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