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疟疾控制的新工具——明智地使用它们。

New tools for malaria control - using them wisely.

机构信息

Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.

出版信息

J Infect. 2017 Jun;74 Suppl 1:S23-S26. doi: 10.1016/S0163-4453(17)30187-1.

Abstract

The incidence of malaria in sub-Saharan Africa is falling and in many countries on the continent the pattern of malaria infection within the country is becoming more heterogeneous. National malaria control programmes need to take this into account and the 'one size fits all' approach to malaria control may no longer be appropriate, with individual approaches being needed in different parts of a country. This applies particularly to decisions on the introduction of new control tools. Recent experience with Seasonal Malaria Chemoprevention and with the RTS,S/AS01 malaria vaccine provides examples of interventions which need to be deployed on a restricted rather than a national basis, taking account of differences in climate and the intensity of malaria infection between regions within a country. Designing, implementing and monitoring more complex national malaria control programmes will require staff skilled in many disciplines, and substantial funding will be needed to sustain these more complex control programmes, even though the burden of the disease is falling.

摘要

撒哈拉以南非洲的疟疾发病率正在下降,在该大陆的许多国家,国内疟疾感染模式变得更加多样化。国家疟疾控制规划需要考虑到这一点,针对疟疾控制的“一刀切”方法可能不再合适,在一个国家的不同地区需要采取不同的方法。这尤其适用于引入新的控制工具的决策。最近在季节性疟疾化学预防和 RTS,S/AS01 疟疾疫苗方面的经验表明,需要根据气候差异和国内各地区疟疾感染强度,在有限的基础上而不是在国家基础上部署这些干预措施。设计、实施和监测更复杂的国家疟疾控制规划将需要多学科技能的工作人员,并且需要大量资金来维持这些更复杂的控制规划,尽管疾病负担正在下降。

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