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植物介导合成银纳米颗粒的机制——关于所涉及的生物分子、表征及抗菌活性的综述

Mechanism of plant-mediated synthesis of silver nanoparticles - A review on biomolecules involved, characterisation and antibacterial activity.

作者信息

Rajeshkumar S, Bharath L V

机构信息

School of Bio-Sciences and Technology, VIT University, Vellore, 632014, TN, India.

School of Bio-Sciences and Technology, VIT University, Vellore, 632014, TN, India.

出版信息

Chem Biol Interact. 2017 Aug 1;273:219-227. doi: 10.1016/j.cbi.2017.06.019. Epub 2017 Jun 21.

Abstract

Engineering a reliable and eco-accommodating methodology for the synthesis of metal nanoparticles is a crucial step in the field of nanotechnology. Plant-mediated synthesis of metal nanoparticles has been developed as a substitute to defeat the limitations of conventional synthesis approaches such as physical and chemical methods. Biomolecules, such as proteins, amino acids, enzymes, flavonoids, and terpenoids from several plant extracts have been used as a stabilising and reducing agents for the synthesis of AgNPs. Regardless of an extensive range of biomolecules assistance in the synthesis procedure, researchers are facing a significant challenge to synthesise stable and geometrically controlled AgNPs. In the past decade, several efforts were made to develop Plant-mediated synthesis methods to produce stable, cost effective and eco-friendly AgNPs. More than hundred different plants extract sources for synthesising AgNPs were described in the last decade by several researchers. Most of the reviews were focused on various plant sources for synthesis, various characterization techniques for characteristic analysis, and antibacterial activity against bacterial. There are many reviews are available for the plant-mediated synthesis of AgNPs as well as antibacterial activity of AgNPs but this is the first review article mainly focused on biomolecules of plants and its various parts and operating conditions involved in the synthesis. Apart from, this review includes the characterisation of AgNPs and antibacterial activity of such nanoparticles with size, shape and method used for this study.

摘要

设计一种可靠且环保的金属纳米颗粒合成方法是纳米技术领域的关键一步。植物介导的金属纳米颗粒合成方法已被开发出来,以克服传统合成方法(如物理和化学方法)的局限性。来自几种植物提取物的生物分子,如蛋白质、氨基酸、酶、黄酮类化合物和萜类化合物,已被用作合成银纳米颗粒的稳定剂和还原剂。尽管在合成过程中有广泛的生物分子辅助,但研究人员在合成稳定且几何形状可控的银纳米颗粒方面仍面临重大挑战。在过去十年中,人们做出了多项努力来开发植物介导的合成方法,以生产稳定、经济高效且环保的银纳米颗粒。在过去十年中,几位研究人员描述了一百多种不同的用于合成银纳米颗粒的植物提取物来源。大多数综述都集中在用于合成的各种植物来源、用于特征分析的各种表征技术以及对细菌的抗菌活性上。关于植物介导的银纳米颗粒合成以及银纳米颗粒的抗菌活性有很多综述,但这是第一篇主要关注植物生物分子及其各个部分以及合成过程中涉及的操作条件的综述文章。此外,本综述包括银纳米颗粒的表征以及此类纳米颗粒的抗菌活性,涉及尺寸、形状以及本研究使用的方法。

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