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利用干细胞氧生理学优化囊胚培养,同时将低氧应激降至最低。

Using stem cell oxygen physiology to optimize blastocyst culture while minimizing hypoxic stress.

机构信息

CS Mott Center for Human Growth and Development, Department of Ob/Gyn, Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, Detroit, MI, 48201, USA.

Department of Obstetrics and Gynecology, Kaleida Women's and Children's Hospital Buffalo New York, Buffalo, NY, USA.

出版信息

J Assist Reprod Genet. 2017 Oct;34(10):1251-1259. doi: 10.1007/s10815-017-0971-x. Epub 2017 Jun 24.

Abstract

This review is a response to the Fellows Forum on testing 2% oxygen for best culture of human blastocysts (J Ass Reprod Gen 34:303-8, 1; J Ass Reprod Gen 34:309-14, 2) prior to embryo transfer. It is a general analysis in support of the position that an understanding of stem cell physiology and responses to oxygen are necessary for optimization of blastocyst culture in IVF and to enhance reproductive success in fertile women.

摘要

这篇综述是对人类囊胚培养中进行 2%氧气检测的论坛(J Ass Reprod Gen 34:303-8, 1;J Ass Reprod Gen 34:309-14, 2)的回应。它是对以下观点的一般性分析,即理解干细胞生理学和对氧气的反应对于优化体外受精中的囊胚培养以及提高生育能力妇女的生殖成功率是必要的。

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