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脑胶质母细胞瘤的额外中枢神经系统转移：新的可能触发事件？

Extra central nervous system metastases from glioblastoma: a new possible trigger event?

机构信息

Neuro Oncology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy.

Neurosurgery Department, Radiotherapy Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.

出版信息

Neurol Sci. 2017 Oct;38(10):1873-1875. doi: 10.1007/s10072-017-3036-0. Epub 2017 Jun 24.

DOI:10.1007/s10072-017-3036-0
PMID:28647829
Abstract

Extra-cranial metastases of glioblastoma (GBM) represent a rare event, and the biological-genetic mechanisms involved in the pathogenesis have not yet been determined. We report the case of a young patient with multiple visceral and osseous metastases occurred after 4 years after first diagnosis of GBM. The strangeness as well as the rarity of this event does not allow to identify an effective treatment for GBM metastases, making the management of this ominous tumor an even greater challenge.

摘要

脑外转移的胶质母细胞瘤（GBM）是一种罕见的现象，其发病的生物学-遗传学机制尚未确定。我们报告了一例年轻患者，在首次诊断为 GBM 后 4 年后出现多个内脏和骨骼转移。这种情况的罕见性使得无法确定有效的 GBM 转移治疗方法，这使得这种凶险肿瘤的治疗更加具有挑战性。

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Neurosurg Rev. 2016 Jan;39(1):37-45; discussion 45-6. doi: 10.1007/s10143-015-0656-9. Epub 2015 Jul 28.
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Antiangiogenic Therapies and Extracranial Metastasis in Glioblastoma: A Case Report and Review of the Literature.胶质母细胞瘤中的抗血管生成疗法与颅外转移：一例病例报告及文献综述
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胶质母细胞瘤患者的骨转移病例系列。
Medicine (Baltimore). 2024 Jul 5;103(27):e38794. doi: 10.1097/MD.0000000000038794.
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