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胶质母细胞瘤的神经外转移且无同时发生的中枢神经系统复发

Extraneural Metastases of Glioblastoma without Simultaneous Central Nervous System Recurrence.

作者信息

Kim Wonki, Yoo Heon, Shin Sang Hoon, Gwak Ho Shin, Lee Seung Hoon

机构信息

Department of Neurosurgery, Seoul National University Hospital, Seoul, Korea.

Neuro-Oncology Clinic, Research Institute and Hospital, National Cancer Center, Goyang, Korea.

出版信息

Brain Tumor Res Treat. 2014 Oct;2(2):124-7. doi: 10.14791/btrt.2014.2.2.124. Epub 2014 Oct 31.

DOI:10.14791/btrt.2014.2.2.124
PMID:25408938
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4231629/
Abstract

Glioblastoma multiforme (GBM) is well known as the most common malignant primary brain tumor. It could easily spread into the adjacent or distant brain tissue by infiltration, direct extension and cerebro-spinal fluid dissemination. The extranueural metastatic spread of GBM is relatively rare but it could have more progressive disease course. We report a 39-year-old man who had multiple bone metastases and malignant pleural effusion of the GBM without primary site recurrence.

摘要

多形性胶质母细胞瘤（GBM）是众所周知的最常见的原发性恶性脑肿瘤。它很容易通过浸润、直接蔓延和脑脊液播散扩散到邻近或远处的脑组织。GBM的神经外转移相对少见，但病程可能更具进展性。我们报告了一名39岁男性，其患有多形性胶质母细胞瘤的多处骨转移和恶性胸腔积液，而原发部位无复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77dd/4231629/74335d3b9ed2/btrt-2-124-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77dd/4231629/2b995010c9fa/btrt-2-124-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77dd/4231629/8cd7fa1a622a/btrt-2-124-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77dd/4231629/ea5cccdba4ae/btrt-2-124-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77dd/4231629/74335d3b9ed2/btrt-2-124-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77dd/4231629/2b995010c9fa/btrt-2-124-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77dd/4231629/8cd7fa1a622a/btrt-2-124-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77dd/4231629/ea5cccdba4ae/btrt-2-124-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77dd/4231629/74335d3b9ed2/btrt-2-124-g004.jpg

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2
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Am J Dermatopathol. 2008 Aug;30(4):381-4. doi: 10.1097/DAD.0b013e31817532c4.
3
Extra central nervous system metastases from cerebral glioblastoma multiforme in elderly patients. Clinico-pathological remarks on our series of seven cases and critical review of the literature.
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Front Oncol. 2023 Feb 16;13:1101552. doi: 10.3389/fonc.2023.1101552. eCollection 2023.
4
Astrocytes-Derived Small Extracellular Vesicles Hinder Glioma Growth.星形胶质细胞衍生的小细胞外囊泡抑制胶质瘤生长。
Biomedicines. 2022 Nov 17;10(11):2952. doi: 10.3390/biomedicines10112952.
5
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6
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5
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