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来自雌性林奈唾液腺蛋白质组分析的数据。

Data from salivary gland proteome analysis of female Linn.

作者信息

Dhawan Rakhi, Mohanty Ajeet Kumar, Kumar Manish, Dey Gourav, Advani Jayshree, Prasad T S Keshava, Kumar Ashwani

机构信息

Department of Community Medicine, Armed Forces Medical College, Pune 411040, India.

National Institute of Malaria Research, Field Station, Goa 403001, India.

出版信息

Data Brief. 2017 May 25;13:274-277. doi: 10.1016/j.dib.2017.05.034. eCollection 2017 Aug.

DOI:10.1016/j.dib.2017.05.034
PMID:28649586
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5470437/
Abstract

Salivary gland proteins from female mosquito were extracted and analyzed on high-resolution mass spectrometry. Proteomic data was analysed using two search algorithms SEQUEST and Mascot, which results in acquisition of 83,836 spectra which were assigned to 5417 peptides belonging to 1208 proteins.These proteins were then assigned molecular functions and further analysis revealed biological processes they are involved in using Gene Ontology annotations. Several immunity related pathways were found to be enriched in salivary gland.The data of this study are also related to the research article "Mosquito-Borne Diseases and Omics: Salivary gland proteome of the female mosquito" (Dhawan et al., 2017) [1]. These data are deposited in ProteomeXchange in the public dataset PXD002468. In addition,a scientific interpretation of this dataset by Dhawan et al. [1] is available at http://dx.doi.org/10.1089/journal.omi.2016.0160.

摘要

提取雌性蚊子唾液腺中的蛋白质,并通过高分辨率质谱进行分析。使用两种搜索算法SEQUEST和Mascot对蛋白质组数据进行分析,结果获得了83836个光谱,这些光谱被分配给属于1208种蛋白质的5417个肽段。然后为这些蛋白质赋予分子功能,进一步分析通过基因本体注释揭示了它们参与的生物学过程。发现唾液腺中几种与免疫相关的途径显著富集。本研究的数据也与研究文章《蚊媒疾病与组学:雌性蚊子的唾液腺蛋白质组》(Dhawan等人,2017年)[1]相关。这些数据存于ProteomeXchange的公共数据集PXD002468中。此外,Dhawan等人[1]对该数据集的科学解读可在http://dx.doi.org/10.1089/journal.omi.2016.0160获取。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a3c/5470437/f71b9d156917/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a3c/5470437/f71b9d156917/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a3c/5470437/f71b9d156917/gr1.jpg

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本文引用的文献

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Mosquito-Borne Diseases and Omics: Salivary Gland Proteome of the Female Aedes aegypti Mosquito.蚊媒疾病与组学:埃及伊蚊雌蚊的唾液腺蛋白质组
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埃及伊蚊气味结合蛋白 22 通过其 C 端尾部的构象变化选择性结合脂肪酸。
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STRING v9.1:蛋白质-蛋白质相互作用网络,具有更高的覆盖度和集成度。
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B2G-FAR, a species-centered GO annotation repository.B2G-FAR,一个以物种为中心的 GO 注释知识库。
Bioinformatics. 2011 Apr 1;27(7):919-24. doi: 10.1093/bioinformatics/btr059. Epub 2011 Feb 18.
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