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子宫内膜异位症症状对工作场所和家庭缺勤和出勤的影响。

The Effect of Endometriosis Symptoms on Absenteeism and Presenteeism in the Workplace and at Home.

机构信息

1 AbbVie, North Chicago, Illinois.

2 Evidera-Evidence, Value & Access by PPD, Bethesda, Maryland.

出版信息

J Manag Care Spec Pharm. 2017 Jul;23(7):745-754. doi: 10.18553/jmcp.2017.23.7.745.

Abstract

BACKGROUND

Characterized by pain symptoms, endometriosis affects women's productivity in their prime working years.

OBJECTIVE

To evaluate the effect of individual endometriosis symptoms on household chore and employment productivity as measured by presenteeism and absenteeism in a population survey of women with endometriosis.

METHODS

An online survey of U.S. women was conducted to evaluate the prevalence of endometriosis, as well as symptoms, demographics, and clinical characteristics of the respondents. Women aged 18-49 years (inclusive) with endometriosis completed the Health-related Productivity Questionnaire to assess presenteeism and absenteeism for employed and household work. Descriptive statistics were used to describe the sample, survey responses, and the effect of endometriosis symptom severity on household chore and employment productivity. Regression analyses were performed to examine the effect of individual endometriosis symptoms on employment and household productivity lost because of presenteeism and absenteeism.

RESULTS

Of 59,411 women who completed the prevalence screener, 5,879 women (9.9%) met the inclusion criteria for completing the survey; 1,318 women (2.2%) reported endometriosis and at least 1 hour of scheduled household chores in the past 7 days. Of these, 810 women had least 1 hour of scheduled employment in the past 7 days. Mean age was 34.6 years (standard error [SE] ± 0.32); 77.2% of the women were white; 59.3% were married or in a civil union; and 59.1% were employed full or part time. Women with endometriosis had a weekly loss of an average of 5.3 hours (SE ± 0.4) because of employment presenteeism, 1.1 hours (SE ± 0.2) of employment absenteeism, 2.3 (SE ± 0.2) hours of household presenteeism, and 2.5 (SE ± 0.2) hours of household absenteeism. Hourly losses in employment and household chore productivity were significantly greater with increasing symptom severity (mild vs. severe: 1.9 vs. 15.8 total employment hours lost and 2.5 vs. 10.1 total household hours lost; P < 0.0001). Women who experienced 3 endometriosis symptoms concurrently lost a significantly greater number of employment hours because of absenteeism and presenteeism compared with those experiencing 1 or 2 symptoms (P < 0.001). Regression analyses showed that a range of endometriosis symptoms predicted employment and household losses because of presenteeism and absenteeism.

CONCLUSIONS

There was a significant relationship between the number and patient-reported severity of endometriosis symptoms experienced and hours of employment and household productivity lost because of presenteeism and absenteeism. Study findings indicate a need for guidance strategies to help women and employers manage endometriosis so as to reduce productivity loss.

DISCLOSURES

The design and financial support for this study was provided by AbbVie. AbbVie participated in data analysis, interpretation of data, review, and approval of the manuscript. Coyne and Gries are employees of Evidera- Evidence, Value & Access by PPD and were paid scientific consultants for AbbVie in connection with this study. Soliman, Castelli-Hayley, and Snabes are AbbVie employees and may own AbbVie stock or stock options. Surrey is affiliated with Colorado Center for Reproductive Medicine and was paid by AbbVie as a consultant for this project. Surrey serves as a consultant for AbbVie outside of this project. All authors participated in data analysis and interpretation, and contributed to the development of the manuscript. The authors maintained control over the final contents of the manuscript and the decision to publish. Study concept and design were contributed by Soliman, Coyne, Gries, and Castelli-Haley. Soliman, Castelli-Haley, Coyne, and Gries collected the data, and data interpretation was performed by Snabes, Surrey, Soliman, Coyne, and Gries. The manuscript was written and revised by Soliman, Coyne, and Gries, along with the other authors.

摘要

背景

子宫内膜异位症的特征是疼痛症状,会影响女性在最佳工作年龄的生产力。

目的

评估个体子宫内膜异位症症状对家务和就业生产力的影响,使用出勤和旷工来衡量子宫内膜异位症患者的人群调查中的生产力。

方法

对美国女性进行了在线调查,以评估子宫内膜异位症的患病率,以及受访者的症状、人口统计学和临床特征。年龄在 18-49 岁(含)之间的患有子宫内膜异位症的女性完成了健康相关生产力问卷,以评估就业和家务劳动的出勤和旷工情况。使用描述性统计数据来描述样本、调查结果以及子宫内膜异位症症状严重程度对家务和就业生产力的影响。进行回归分析以检查个体子宫内膜异位症症状对因出勤和旷工而导致的就业和家务劳动生产力损失的影响。

结果

在完成患病率筛查的 59411 名女性中,有 5879 名女性(9.9%)符合完成调查的纳入标准;1318 名女性(2.2%)报告了子宫内膜异位症,并且在过去 7 天内至少有 1 小时的计划家务劳动。其中,810 名女性在过去 7 天内至少有 1 小时的计划就业。平均年龄为 34.6 岁(标准误差[SE]±0.32);77.2%的女性为白人;59.3%已婚或处于民事结合关系;59.1%全职或兼职就业。患有子宫内膜异位症的女性因就业出勤而每周平均损失 5.3 小时(SE±0.4),因就业旷工而损失 1.1 小时(SE±0.2),因家务出勤而损失 2.3 小时(SE±0.2),因家务旷工而损失 2.5 小时(SE±0.2)。随着症状严重程度的增加,就业和家务劳动生产力的小时损失明显更大(轻度与重度:总就业时间损失 1.9 与 15.8 小时,总家务时间损失 2.5 与 10.1 小时;P<0.0001)。同时经历 3 种子宫内膜异位症症状的女性因旷工和出勤而导致的就业时间损失明显大于仅经历 1 种或 2 种症状的女性(P<0.001)。回归分析显示,一系列子宫内膜异位症症状预测了因旷工和出勤而导致的就业和家务劳动损失。

结论

子宫内膜异位症症状的数量和患者报告的严重程度与旷工和出勤导致的就业和家务劳动生产力损失小时数之间存在显著关系。研究结果表明,需要有指导策略来帮助女性和雇主管理子宫内膜异位症,以减少生产力损失。

披露

这项研究的设计和资金支持由 AbbVie 提供。AbbVie 参与了数据分析、数据解释、审查和对本手稿的批准。Coyne 和 Gries 是 Evidera- Evidence, Value & Access by PPD 的员工,在与本研究相关的情况下,他们是 AbbVie 的付费科学顾问。Soliman、Castelli-Hayley 和 Snabes 是 AbbVie 的员工,他们可能拥有 AbbVie 的股票或股票期权。Surrey 隶属于科罗拉多生殖医学中心,并由 AbbVie 支付费用作为本项目的顾问。Surrey 在本项目之外还担任 AbbVie 的顾问。所有作者均参与了数据分析和解释,并为手稿的撰写和修订做出了贡献。研究概念和设计由 Soliman、Coyne、Gries 和 Castelli-Haley 贡献。Soliman、Castelli-Haley、Coyne 和 Gries 收集了数据,Snabes、Surrey、Soliman、Coyne 和 Gries 进行了数据解释。手稿由 Soliman、Coyne 和 Gries 与其他作者一起撰写和修订。

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