Martins Isabelle, Raza Syed Qasim, Voisin Laurent, Dakhli Haithem, Law Frédéric, De Jong Dorine, Allouch Awatef, Thoreau Maxime, Brenner Catherine, Deutsch Eric, Perfettini Jean-Luc
Cell Death and Aging Team, Gustave Roussy Cancer Campus, Villejuif, France; Laboratory of Molecular Radiotherapy, INSERM U1030, Gustave Roussy Cancer Campus, Villejuif, France; Gustave Roussy Cancer Campus, Villejuif, France; Paris-Saclay University, Villejuif, France.
Laboratory of Signalling and Cardiovascular Pathophysiology, INSERM UMR-S 1180, Paris-Sud University, Chatenay-Malabry, France.
Biomed J. 2017 Jun;40(3):133-140. doi: 10.1016/j.bj.2017.05.001. Epub 2017 May 31.
The present review summarizes recent experimental evidences about the existence of the non-cell-autonomous death entosis in physiological and pathophysiological contexts, discusses some aspects of this form of cell death, including morphological, biochemical and signaling pathways that distinguish non-cell-autonomous demises from other death modalities and propose to define this new modality of death as type IV programmed cell death.
本综述总结了关于在生理和病理生理背景下非细胞自主性死亡吞噬作用存在的近期实验证据,讨论了这种细胞死亡形式的一些方面,包括将非细胞自主性死亡与其他死亡方式区分开来的形态学、生物化学和信号通路,并提议将这种新的死亡方式定义为IV型程序性细胞死亡。