McKeigue P M, Marmot M G, Adelstein A M, Hunt S P, Shipley M J, Butler S M, Riemersma R A, Turner P R
Lancet. 1985 Nov 16;2(8464):1086-90. doi: 10.1016/s0140-6736(85)90684-1.
Asian immigrants to England and Wales have high mortality from coronary heart disease but low mortality from colon cancer. A survey of Asians in the London boroughs of Brent and Harrow was undertaken with the object of investigating this. Compared with the British population, the Asians consumed less saturated (S) fat and cholesterol and more polyunsaturated (P) fat and vegetable fibre. The P/S ratio of the Asians' diet was 0.85 compared with 0.28 in the British population: this was reflected in the very high linoleic acid content of their plasma lipids. The plasma total cholesterol and high-density-lipoprotein cholesterol of Asian men was similar to that of a British comparison group; the concentrations in Asian women were much lower than in British women. Smoking rates were low in both Asian men and Asian women. The high rates of coronary heart disease in Asian immigrants are not explained by the levels of these risk factors.
移民到英格兰和威尔士的亚洲人冠心病死亡率高,但结肠癌死亡率低。为此,对布伦特和哈罗这两个伦敦行政区的亚洲人进行了一项调查。与英国人群相比,亚洲人摄入的饱和(S)脂肪和胆固醇较少,而多不饱和(P)脂肪和蔬菜纤维较多。亚洲人饮食的P/S比值为0.85,而英国人群为0.28:这反映在他们血浆脂质中亚油酸含量非常高。亚洲男性的血浆总胆固醇和高密度脂蛋白胆固醇与英国对照组相似;亚洲女性的浓度远低于英国女性。亚洲男性和女性的吸烟率都很低。这些风险因素的水平并不能解释亚洲移民中冠心病的高发病率。