Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.
Japanese Red Cross Ogawa Hospital, Saitama, Japan.
Geriatr Gerontol Int. 2017 Dec;17(12):2602-2609. doi: 10.1111/ggi.13119. Epub 2017 Jun 28.
We compared skeletal muscle mass and physical function between older adults with sarcopenia and those with sarcopenic obesity.
Body composition and physical and cognitive function were measured for 1283 community-dwelling older adults. Participants responded to questionnaires about pain and exercise. The pure sarcopenia group (PS) included individuals with sarcopenia only. The sarcopenic obesity group (SO) included individuals with both sarcopenia and obesity. Groups were compared after adjusting for sex, age and height through propensity score matching.
The PS and SO included 129 and 105 individuals, respectively. Comorbidities were more frequent in the SO (P < 0.001). The SO had higher upper limb muscle mass (P < 0.001), and had lower ratios of lower limb muscle mass to upper limb muscle mass (P < 0.001) and of lower limb muscle mass to weight (P < 0.001). The SO also had poorer grip power (P = 0.007), gait times (usual pace, P = 0.001; maximum speed, P = 0.001), Timed Up and Go test (P < 0.001), and time standing on one foot (P = 0.005) than the PS. The SO had a higher frequency of gonalgia (P = 0.013). After adjusting for covariates, comorbidities, upper limb muscle mass, lower limb muscle mass to upper limb muscle mass ratio, lower limb muscle mass to weight ratio, gait time, Timed Up and Go test, time standing on one foot, and gonalgia differed significantly between the PS and SO.
Sarcopenic obesity decreases the ratio of lower limb muscle mass to weight by increasing weight. It affects physical function in older Japanese adults with low weight. Decreased relative lower limb muscle mass is an important function-limiting factor in sarcopenic obesity. Geriatr Gerontol Int 2017; 17: 2602-2609.
我们比较了患有肌少症和肌少症合并肥胖症的老年人之间的骨骼肌量和身体功能。
对 1283 名社区居住的老年人进行了身体成分和身体及认知功能的测量。参与者回答了有关疼痛和运动的问卷。单纯性肌少症组（PS）包括仅患有肌少症的个体。肌少症合并肥胖症组（SO）包括同时患有肌少症和肥胖症的个体。通过倾向评分匹配，在调整性别、年龄和身高后对各组进行比较。
PS 和 SO 分别包括 129 名和 105 名个体。SO 组合并症更为常见（P<0.001）。SO 组上肢肌肉量较高（P<0.001），下肢肌肉量与上肢肌肉量的比值（P<0.001）和下肢肌肉量与体重的比值（P<0.001）较低。SO 组握力（P=0.007）、步速（常规速度，P=0.001；最大速度，P=0.001）、计时起立行走测试（TUGT）（P<0.001）和单脚站立时间（P=0.005）均较差。SO 组出现臀痛的频率较高（P=0.013）。在调整协变量、上肢肌肉量、下肢肌肉量与上肢肌肉量的比值、下肢肌肉量与体重的比值、步速、TUGT、单脚站立时间和臀痛后，PS 和 SO 之间在合并症、上肢肌肉量、下肢肌肉量与上肢肌肉量的比值、下肢肌肉量与体重的比值、步速、TUGT、单脚站立时间和臀痛方面有显著差异。
肌少症合并肥胖症通过增加体重降低了下肢肌肉量与体重的比值。它影响了日本低体重老年人的身体功能。相对下肢肌肉量减少是肌少症合并肥胖症的一个重要的功能受限因素。老年医学与老年健康学杂志 2017；17：2602-2609。
