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Human brucellosis in South Africa: Public health and diagnostic pitfalls.南非的人类布鲁氏菌病:公共卫生与诊断陷阱
S Afr Med J. 2016 Aug 1;106(9):883-5. doi: 10.7196/SAMJ.2016.v106i9.11020.
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Knowledge and attitude towards zoonoses among animal health workers and livestock keepers in Arusha and Tanga, Tanzania.坦桑尼亚阿鲁沙和坦噶地区动物卫生工作者及牲畜饲养者对人畜共患病的认知与态度
Tanzan J Health Res. 2010 Oct;12(4):280-6. doi: 10.4314/thrb.v12i4.54709.
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Seroprevalence of brucellosis and risk factors related to high risk occupational groups in Kazeroon, South of Iran.伊朗南部卡泽伦布鲁氏菌病血清流行率及高危职业群体相关危险因素
Int J Occup Environ Med. 2010 Apr;1(2):62-8.
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Epidemiological and clinical aspects of human Brucella suis infection in Polynesia.人类感染猪布鲁氏菌在波利尼西亚的流行病学和临床方面。
Epidemiol Infect. 2011 Oct;139(10):1621-5. doi: 10.1017/S0950268811001075. Epub 2011 Jun 21.
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Serological diagnosis of brucellosis.布鲁氏菌病的血清学诊断
Prilozi. 2010;31(1):65-89.
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Brucella serology in abattoir workers.屠宰场工人的布鲁氏菌血清学
J Ayub Med Coll Abbottabad. 2008 Jul-Sep;20(3):57-61.
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Risk factors for brucellosis in Samarqand Oblast, Uzbekistan.乌兹别克斯坦撒马尔罕州布鲁氏菌病的危险因素。
Int J Infect Dis. 2009 Nov;13(6):749-53. doi: 10.1016/j.ijid.2009.02.014. Epub 2009 May 19.
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Human brucellosis: seroprevalence and risk factors related to high risk occupational groups in Tanga Municipality, Tanzania.人类布鲁氏菌病:坦桑尼亚坦噶市高危职业群体的血清阳性率及相关风险因素
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Health-seeking behaviour of human brucellosis cases in rural Tanzania.坦桑尼亚农村地区人类布鲁氏菌病病例的就医行为。
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Epidemiology and risk factors of brucellosis in Alexandria governorate.亚历山大省布鲁氏菌病的流行病学及危险因素
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家畜养殖专业人员中人类布鲁氏菌病的患病率及相关因素

Prevalence and factors associated with human brucellosis in livestock professionals.

作者信息

Mufinda Franco Cazembe, Boinas Fernando, Nunes Carla

机构信息

Escola Nacional de Saúde Pública. Universidade Nova de Lisboa. Lisboa, Portugal.

Direcção Provincial de Saúde do Namibe-Angola. Moçâmedes, Namibe, Angola.

出版信息

Rev Saude Publica. 2017 Jun 22;51:57. doi: 10.1590/S1518-8787.2017051006051.

DOI:10.1590/S1518-8787.2017051006051
PMID:28658364
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5493365/
Abstract

OBJECTIVE

The objective of this study is to estimate the seroprevalence of human brucellosis in livestock professionals and analyze the factors associated with brucellosis focusing on sociodemographic variables and the variables of knowledge and practices related to the characteristics of the activities carried out in livestock.

METHODS

This is a cross-sectional seroepidemiological study with a population of 131 workers of butchers, slaughter rooms, and slaughterhouse and 192 breeders sampled randomly in Namibe province, Angola. The data were obtained from the collection of blood and use of questionnaires. The laboratory tests used were rose bengal and slow agglutination. The questionnaire allowed us to collect sociodemographic information and, specifically on brucellosis, it incorporated questions about knowledge, attitudes, and behaviors of livestock professionals. In addition to the descriptive statistical approach, we used the Chi-square test of independence, Fisher's test, and logistic regression models, using a significance level of 10%.

RESULTS

The general weighted prevalence of brucellosis was 15.6% (95%CI 13.61-17.50), being it 5.3% in workers and 16.7% (95%CI 11.39-21.93) in breeders. The statistical significance was observed between human seroprevalence and category (worker and breeder) (p < 0.001) and education level (p = 0.032), start of activity (p = 0079), and service location (p = 0.055). In a multivariate context, the positive factor associated with brucellosis in professionals was the professional category (OR = 3.54; 95%CI 1.57-8.30, related to breeders in relation to workers).

CONCLUSIONS

Human brucellosis in livestock professionals is prevalent in Namibe province (15.6%), where the professional category was the most important factor. The seroprevalence levels detected are high when compared with those found in similar studies.

OBJECTIVO

Estimar a seroprevalência da brucelose humana em profissionais da pecuária e analisar os factores associados à brucelose com foco em variáveis sociodemográficas, de conhecimento e práticas relativas às características das actividades desenvolvidas na pecuária.

MÉTODOS: Estudo transversal seroepidemiológico em população de 131 trabalhadores de talhos, salas de abate e matadouro e 192 criadores amostrados aleatoriamente na província do Namibe, Angola. Os dados foram obtidos por meio de colheita de sangue e aplicação de questionário. Os testes laboratoriais utilizados foram o Rosa de Bengala e a aglutinação lenta em tubos. O questionário permitiu recolher informação sociodemográfica e, especificamente sobre a brucelose, incorporou questões sobre conhecimento, atitudes e comportamentos dos profissionais da pecuária. Além da abordagem estatística descritiva, foram utilizados os testes de Independência do Qui-quadrado, Fisher e modelos de regressão logística, utilizando um nível de significância de 10%.

RESULTADOS

A prevalência geral ponderada da brucelose foi de 15.6% (IC95% 13.61-17.50), sendo 5.3% em trabalhadores e 16.7% (IC95% 11.39-21.93) em criadores. A significância estatística foi observada entre a seroprevalência humana e a categoria (trabalhador e criador) (p < 0.001) e o nível de instrução (p = 0.032), início de actividade (p = 0.079) e local de serviço (p = 0.055). Em um contexto multivariado, o factor positivamente associado à brucelose em profissionais foi a categoria profissional (OR = 3.54; IC95% 1.57-8.30, relativo aos criadores em relação a trabalhadores).

CONCLUSÕES: A brucelose humana em profissionais da pecuária é prevalente na província do Namibe (15.6%), onde a categoria profissional foi o factor mais relevante. Os níveis de seroprevalência detectados são elevados se comparados com outros encontrados em estudos semelhantes.

摘要

目的

本研究的目的是估计畜牧专业人员中人类布鲁氏菌病的血清流行率,并分析与布鲁氏菌病相关的因素,重点关注社会人口统计学变量以及与畜牧活动特征相关的知识和实践变量。

方法

这是一项横断面血清流行病学研究,对安哥拉纳米贝省随机抽取的131名屠夫、屠宰场和屠宰厂工人以及192名饲养员进行了调查。数据通过采血和问卷调查获得。所使用的实验室检测方法是孟加拉玫瑰红试验和试管凝集试验。该问卷使我们能够收集社会人口统计学信息,特别是关于布鲁氏菌病的信息,其中包含了关于畜牧专业人员的知识、态度和行为的问题。除了描述性统计方法外,我们还使用了卡方独立性检验、费舍尔检验和逻辑回归模型,显著性水平为10%。

结果

布鲁氏菌病的总体加权流行率为15.6%(95%置信区间13.61 - 17.50),工人中的流行率为5.3%,饲养员中的流行率为16.7%(95%置信区间11.39 - 21.93)。在人类血清流行率与类别(工人和饲养员)(p < 0.001)、教育水平(p = 0.032)、活动开始时间(p = 0.079)和服务地点(p = 0.055)之间观察到统计学显著性。在多变量情况下,与专业人员布鲁氏菌病相关的积极因素是专业类别(比值比 = 3.54;95%置信区间1.57 - 8.30,饲养员相对于工人)。

结论

纳米贝省畜牧专业人员中的人类布鲁氏菌病流行率为15.6%,其中专业类别是最重要的因素。与类似研究中发现的流行率相比,检测到的血清流行率水平较高。

目的

估计畜牧专业人员中人类布鲁氏菌病的血清流行率,并分析与布鲁氏菌病相关的因素,重点关注社会人口统计学变量以及与畜牧活动特征相关的知识和实践变量。

方法

在安哥拉纳米贝省对131名屠夫、屠宰场和屠宰厂工人以及192名饲养员进行随机抽样的横断面血清流行病学研究。数据通过采血和问卷调查获得。所使用的实验室检测方法是孟加拉玫瑰红试验和试管凝集试验。该问卷允许收集社会人口统计学信息,特别是关于布鲁氏菌病的信息,其中纳入了关于畜牧专业人员的知识、态度和行为的问题。除了描述性统计方法外,还使用了卡方独立性检验、费舍尔检验和逻辑回归模型,显著性水平为10%。

结果

布鲁氏菌病的总体加权流行率为15.6%(95%置信区间13.61 - 17.50),工人中的流行率为5.3%,饲养员中的流行率为16.7%(95%置信区间11.39 - 21.93)。在人类血清流行率与类别(工人和饲养员)(p < 0.001)、教育水平(p = 0.032)、活动开始时间(p = 0.079)和服务地点(p = 0.055)之间观察到统计学显著性。在多变量情况下,与专业人员布鲁氏菌病相关的积极因素是专业类别(比值比 = 3.54;95%置信区间1.57 - 8.30,饲养员相对于工人)。

结论

纳米贝省畜牧专业人员中的人类布鲁氏菌病流行率为15.6%,其中专业类别是最相关的因素。与其他类似研究中发现的流行率相比,检测到的血清流行率水平较高。