Yusuf Abdulkarim A, Hassan-Kadle Ahmed A, Ibrahim Abdalla M, Hassan-Kadle Mohamed A, Yasin Abdullahi M, Khojaly Maha, Garcia João L, Vieira Rafael F C
Vector-Borne Diseases Laboratory, Department of Veterinary Medicine, Universidade Federal Do Paraná, Curitiba, Brazil.
Abrar Research and Training Centre, Abrar University, Mogadishu, Somalia.
Front Reprod Health. 2021 Aug 4;3:672885. doi: 10.3389/frph.2021.672885. eCollection 2021.
Toxoplasmosis and brucellosis are zoonotic diseases of worldwide distribution. They both cause abortion and infertility in human and animals. Limited data are available about these pathogens in Somali people and their animals. Hence, this study has evaluated the prevalence of anti- and anti- spp. antibodies in pregnant women in Mogadishu, Somalia. Serum samples from 307 pregnant women from Mogadishu, Somalia were tested for anti- antibodies by Latex Agglutination Test (LAT) and anti- spp. antibodies by Rose Bengal Plate Test (RBPT) and a commercial competitive-ELISA (cELISA). A total of 119/307 (38.76%) pregnant women had a prior history of abortion. A total of 159/307 (51.79%; 95% CI: 46.2-57.35%) pregnant women were seroreactive for by LAT at different stages of pregnancy. For spp., when RBPT and cELISA were combined 4/307 (1.30%; 95% CI: 0.36-3.30%) pregnant women were seroreactive to anti- spp. antibodies, being 2/307 (0.65%; 95% CI: 0.18-2.34%) by RBPT and 3/307 (0.98%; 95% CI: 0.33-2.83%) by cELISA. Two women were seroreactive for both agents. A high seropositivity to and low seropositivity to spp. have been found in pregnant women from Mogadishu, Somalia. Considering the high number of abortions in the country associated to the fact that awareness on other zoonotic abortifacient pathogens in Somalis is very low, further studies should be conducted to evaluate the potential causes of abortions.
弓形虫病和布鲁氏菌病是全球分布的人畜共患病。它们都会导致人和动物流产及不育。关于索马里人和他们动物体内这些病原体的数据有限。因此，本研究评估了索马里摩加迪沙孕妇中抗 和抗 属抗体的流行情况。采用乳胶凝集试验（LAT）检测了来自索马里摩加迪沙的307名孕妇血清样本中的抗 抗体，并采用玫瑰红平板试验（RBPT）和商业竞争酶联免疫吸附测定（cELISA）检测了抗 属抗体。共有119/307（38.76%）孕妇有过流产史。共有159/307（51.79%；95%置信区间：46.2 - 57.35%）孕妇在妊娠不同阶段LAT检测显示对 呈血清反应阳性。对于 属，当RBPT和cELISA联合检测时，4/307（1.30%；95%置信区间：0.36 - （此处原文有误，应为3.30%）3.30%）孕妇对抗 属抗体呈血清反应阳性，其中RBPT检测为2/307（0.65%；95%置信区间：0.18 - 2.34%），cELISA检测为3/307（0.98%；95%置信区间：0.33 - 2.83%）。有两名妇女对两种病原体均呈血清反应阳性。在索马里摩加迪沙的孕妇中发现对 血清阳性率高，而对 属血清阳性率低。鉴于该国流产数量众多，且索马里人对其他导致流产的人畜共患病原体的认识非常低，应进一步开展研究以评估流产的潜在原因。
